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Blood Bank Quiz 2
Donation, Transfusion, etc
| Question | Answer |
|---|---|
| 2 main reasons for donor screening | To ensure safety of donation for donor & to obtain blood that is safe for recipient (no diseases) |
| 2 most important steps of donor collection | Donor screening & arm preparation |
| Can donors be paid for donating blood products for transfusion? | Nope |
| 4 main blood components | RBCs, plasma, cryoprecipitate, and platelets |
| Requirements for RBC products | Stored at 1-6 C for 21-42 days, Average vol: 250-300 mL, QC; Hct <80% |
| Requirements for FFP products | Stored at -18C for 1 year, 1-6 C for 24 hrs. Average vol: 200-250 mL, QC: frozen within 8 hours of collection |
| Requirements for Cryo | Stored at -18C for 1 year, Thawed: 6 hours (single), 4 hours (pooled) at 20-24C. Average vol: 10-25 mL. QC: 150 mg/dL fibrinogen and 80 IU Factor VIII |
| Requirements for Platelets (Random) | Store at 20-24 C (agitate) for 5 days or 4 hours (pooled). Average vol: 50-70 mL. QC: 5.5x10^10 |
| Requirements for Platelets (Apheresis) | Store at 20-24C for 5 days. Average vol: 200-400 mL. QC: >3.0 x10^11 |
| What is the most common transfusion -transmitted infection? | Bacterial contamination |
| 4 "Rights" of Transfusion Therapy | Product, dose, time, and reasons. |
| What is the most important thing for the Blood Bank and the transfusing caregiver to check | Positive patient ID (clerical) |
| Effect of transfused RBCs on H/H | Raise Hgb 1 g/dL and Hct 3% |
| Indications for RBC transfusion | To increase O2 carrying capacity, Hbg <7 g/dL or Hct <21%, and blood loss |
| Platelets raise patient count by _____________. | 20,000-60,000 /uL |
| Indications for cryoprecipitate | Low fibrinogen, Factor XIII deficiency, and DIC |
| Should plasma be given for a hemophiliac patient? | No – or only if no Factor VIII concentrate available |
| Indications for plasma transfusion | Acute blood loss (loss of coag factors) |
| Indications for platelet transfusion | Acute blood loss. Need platelets for form initial clot for coag factors to build upon. |
| Blood products that can be leukoreduced | RBCs and Platelets |
| Indications for Leukoreduced blood product | To prevent FNHTR, reduce risk of CMV transmission, and prevent/delay HLA antibodies |
| Maximum number of WBCs after leukoreduction | 5 x 10^6 |
| Blood products that can be irradiated | Platelets, RBCs, and Granulocytes |
| Indications for irradiation | Prevent GVHD (in immunocompromised) or if receiving transfusion from first degree relative (similarity of HLA antigens on lymphocytes) |
| Unit expires within _______ days of irradiation | 28 (or less) |
| What product should be given to a patient with a previous anaphylactic reaction? | Washed RBCs or platelets, or products from IgA deficient donor |
| What RBC product should be given to neonates? | Fresh, CMV neg or leukoreduced |
| What should be done first if transfusion reaction is suspected? | Stop transfusion immediately |
| What 4 "tests" should be performed if a transfusion reaction is suspected? | Clerical check, Visual inspection, ABO, and DAT |
| What can be done to prevent transfusion associated GVHD? | Irradiation |
Created by:
tessj
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