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Blood Bank Quiz 2

Donation, Transfusion, etc

2 main reasons for donor screening To ensure safety of donation for donor & to obtain blood that is safe for recipient (no diseases)
2 most important steps of donor collection Donor screening & arm preparation
Can donors be paid for donating blood products for transfusion? Nope
4 main blood components RBCs, plasma, cryoprecipitate, and platelets
Requirements for RBC products Stored at 1-6 C for 21-42 days, Average vol: 250-300 mL, QC; Hct <80%
Requirements for FFP products Stored at -18C for 1 year, 1-6 C for 24 hrs. Average vol: 200-250 mL, QC: frozen within 8 hours of collection
Requirements for Cryo Stored at -18C for 1 year, Thawed: 6 hours (single), 4 hours (pooled) at 20-24C. Average vol: 10-25 mL. QC: 150 mg/dL fibrinogen and 80 IU Factor VIII
Requirements for Platelets (Random) Store at 20-24 C (agitate) for 5 days or 4 hours (pooled). Average vol: 50-70 mL. QC: 5.5x10^10
Requirements for Platelets (Apheresis) Store at 20-24C for 5 days. Average vol: 200-400 mL. QC: >3.0 x10^11
What is the most common transfusion -transmitted infection? Bacterial contamination
4 "Rights" of Transfusion Therapy Product, dose, time, and reasons.
What is the most important thing for the Blood Bank and the transfusing caregiver to check Positive patient ID (clerical)
Effect of transfused RBCs on H/H Raise Hgb 1 g/dL and Hct 3%
Indications for RBC transfusion To increase O2 carrying capacity, Hbg <7 g/dL or Hct <21%, and blood loss
Platelets raise patient count by _____________. 20,000-60,000 /uL
Indications for cryoprecipitate Low fibrinogen, Factor XIII deficiency, and DIC
Should plasma be given for a hemophiliac patient? No – or only if no Factor VIII concentrate available
Indications for plasma transfusion Acute blood loss (loss of coag factors)
Indications for platelet transfusion Acute blood loss. Need platelets for form initial clot for coag factors to build upon.
Blood products that can be leukoreduced RBCs and Platelets
Indications for Leukoreduced blood product To prevent FNHTR, reduce risk of CMV transmission, and prevent/delay HLA antibodies
Maximum number of WBCs after leukoreduction 5 x 10^6
Blood products that can be irradiated Platelets, RBCs, and Granulocytes
Indications for irradiation Prevent GVHD (in immunocompromised) or if receiving transfusion from first degree relative (similarity of HLA antigens on lymphocytes)
Unit expires within _______ days of irradiation 28 (or less)
What product should be given to a patient with a previous anaphylactic reaction? Washed RBCs or platelets, or products from IgA deficient donor
What RBC product should be given to neonates? Fresh, CMV neg or leukoreduced
What should be done first if transfusion reaction is suspected? Stop transfusion immediately
What 4 "tests" should be performed if a transfusion reaction is suspected? Clerical check, Visual inspection, ABO, and DAT
What can be done to prevent transfusion associated GVHD? Irradiation
Created by: tessj