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ASCP Study coagualtion & hematology

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Chemicals that prevent blood from clotting are called what?   Anticoagulants  
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Platelet peripheral zone is responsible for   Adhesion  
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Platelet Solu-Gel zone is responsible for   Contraction  
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Platelet organelle zone is responsible for   Secretion  
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Bernard Soulier syndrome   Platelet disorder with giant platelets causes a deficiency of Glycoprotein 1b a receptor for Von W Factor  
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Count for platelets in hemocytometer    
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The term used to indicate that a wound has stopped bleeding is?   Hemostasis  
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Chemicals released from a vein by injury are called?   Vascular Factors  
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Chemicals released by platelets to induce narrowing of the blood vessel are known as?   Platelet Factor  
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Chemicals in the plasma that stops blood clotting are called?   Plasma Factor  
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All the individual blood factors will cause?   Vasoconstriction  
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Vascular Factor is also called?   Von Wilebrand's Factor  
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The messenger for platelets to aggregate at an injury site is?   Vascular Factor  
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The test for Von Wilebrands factor is the   Bleeding Time  
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Bleeding time test determines a deficiency in which factor   Vascular or Von Wilebrands  
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What is the normal value for the Bleeding Time?   less than 7.5 minutes  
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What is the test that replaces the BT   PFA or PFT Platelet Function Assay/Test  
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What changes to platelets does Vascular Factor affect?   Platelets grow fingers & become sticky  
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A hemostatic plug is made up of what?   platelet aggregates  
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Normally platelets are not sticky & don't adhere to vessel walls. When sticky, where do they adhere (anatomical)   Tunica media and adventitia  
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The outer layer of a vein is the...   Tunica adventia  
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The middle layer of a vein is the...   Tunica media  
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The inner layer of a vein is the...   Tunica intima  
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Which coagulation test is for platelet function?   PT Prothrombin  
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In what tube is the PT test drawn?   Light blue  
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What is a normal range for the PT?   10-12 seconds  
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What drugs are used to reduce clotting in patients with a disorder of platelets?   Coumadin or Warfarin  
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Does the PT test for Intrinsic or Extrinsic factors   Extrinsic  
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What is the INR   International Normalized Results  
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What is the normal INR result?   between 0.9 and 1.1 INR  
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The formula for INR is...   Patient Results divided by the International normal.  
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When drawing blood from a patient on anticoagulants what is of concern?   bruising or hematoma  
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What is the test for Plasma Factors?   PTT Partial Thromboplastin time  
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PTT test is used to monitor patients on which anticoagulant?   Heparin  
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What is the normal value for a PTT?   28-34 seconds  
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7.5 minutes or less is normal value for which test?   BT  
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10 - 20 seconds is a normal range for which test?   PT  
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28 - 24 seconds is a normal range for which test?   PTT  
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PT screens for abnormal blood coagulation triggered by exposure of plasma to what?   Negatively charged surface  
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Platelets are receptive to what protein?   Fibrinogen  
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Aggregated platelets will combine with what to secure the hemostatic plug?   Fibrin strands  
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The final steps in forming a clot is to activate a mechanism to contract?   Platelet actomyosin  
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Von Wilebrands factor is found in which 2 places?   Plasma and vessel wall  
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