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Bio 361 part 4

sensory receptors

-allow cells to isolate themselves from the environment, this gives them control over their intracellular conditions
lipid bilayer phospholipids
purpose of sphingolipids alter electrical properties
purpose of glycolipids communication between cells
purpose of cholesterol increases membrane fluidity
integral membrane proteins tightly bound to the membrane, either embedded in bilayer or spanning entire bilayer. Consist of aplha helix passes or beta barrels
peripheral proteins weaker association to the bilayer. May have glycolipid anchor
high membrane permeability for these molecules gases and small uncharged polar molecules
some membrane permeability for these molecules water and urea
no membrane permeability for these molecules ions, large uncharged polar molecules, charged polar molecules
Types of membrane protiens -ATP-powered pump
the 3 main types of membrane transport -passive diffusion....use Gradient-facilitated diffusion...uses transport protiens and gradient-active transport...use ENERGY and transport protiens
passive diffusion who and how -lipid soluble molecules
membrane potential electrical gradient across a cell membrane
facilitated diffusion who and how -hydrophobic molecules (amino acids, nucleosides, sugars)
Ion channels form pores-channel has to be open to work
voltage gated ion channels open in response to change in membrane potential
ligand gated ion channels open in response to binding of specific regulatory molecules
mechanically gated ion channels regulated through interaction with subcellular proteins
porins are like ion channels but for bigger molecules....ex aquaporin for H2O
Permeases function more like enzymes. Bind the substance and then undergoes a confirmation change which causes the carrier to release the substrate on other side....ex glucose permease
GLUT1 -a uniporter of glucose
some points on electrical gradients -all transport processes affect chemical gradients
electroneutral carriers transport uncharged molecules or exchange a equal number of charged particles
electrogenic carriers transfer a charge ex NA+/K+ ATPase
Created by: haileyfancher



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