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Hema. WBC Variations

Hematology Variations in WBCs Morphology

Cells showing a variations in morphology in an abnormal response to a stimulus are... Pathological
Cells show variation in morphology but no physiological impairment results. Non-Pathological
Cells show variation in morphology as a normal body response to invasion by a bacteria or virus. Reactive
Neutrophils with more than 6 lobes are defined as HYPERsegmented
Why do hypersegs form? DNA production defect slows production down & the nucleus forms many lobes.
True or False Hypersegmented Neutrophilic cell size remains the same with hypersegmentation. False. They can become larger than 15 microns
The cytoplasm of Hypersegmented neutrophils is less funtional. True or False False. They cytoplasm is normal in appearance and is still phagocytic.
Barr bodies are significant only when? In diseases of chromosomal abnormailities.
Disease conditions of hypersegmented neutrophils include Megaloblastic anemias (Folic acid deficency, or pernicious anemia), cancer therapy, chronic infections.
Created by: Ladybug9537
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