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Classical Condition
Physiology of Behavior Ch 13 Neurology
Question | Answer |
---|---|
The ____ is part of an important system involved in a particular form of stimulus-response learning: classically conditioned emotional responses. | amygdala |
An aversive stimulus produces a | bahavioral, autonomic, and hormonal response. |
LeDoux, Sakaguchi, and Reis | found that a conditioned emotional response can occur in the absence of the auditory cortex. |
If a tone is pared with the painful stimulus | the weak synapses in the lateral amygdala are stregthened through the action of the Hebb rule. |
Quirk, Repa, and LeDoux | found evidence for the synaptic changes in the lateral nucleus of the amygdala. |
Synaptic changes in the lateral nucleus of the amygdala experiment involved | recording activity of neurons before during and after pairing a tone with a foot shock. |
Firing rate of neurons in the lateral amygdala increase | during conditioning. |
Firing rate of neurons in the lateral amygdala decrease | during extinction. |
Changes in the lateral amygdala reosible for acquisition of a conditioned emotional response involve | LTP. |
The amygdala follows the | Hebbian Rule. |
Synapse strengthening by pariing of CS and US happens in the | lateral nucleus of the amygdala. |
Conditioned emotional responses take place in the | hypothalamus, midbrain, pons, and medulla. |
The lateral nucleus outputs to the | basal nucleus, accessory basal nucleus, and the central nucleus. |
The basal nucleus outputs to the | central nucleus. |
The accessory basal nucleus out puts to the | central nucleus. |
The central nucleus outputs to several places including the hypothalamus, midbrain, pons, and medulla causing a | conditioned emotional response. |
LTP in many parts of the brain is accomplished through the | activation of NMDA receptors. |
NMDA receports also participate in the | synaptic plasticity that occurs in the amygdala. |
Learning causes | AMPA receptors to be driven in to dendritic spines of synapses between lateral amygdala neurons and axons that provide auditory input. |
Rodrigues | used a drug that prevents the autophosphorylation of CaM-KII. |
Collins and Pare | found that differential conditioning may produce both long term potentiation and long term depression in the lateral amygdala. |
Experiment: showing the differential conditioning may produce both LTP and LTD | Electrical recordings of the activity of single neurons in the lateral amygdala showed that after learning had taken place, the CS+ elicited a larger response, white the CS- showed a smaller response. |
Schafe and LeDoux | LTP is essential for stimulus response learning. |
Anisomycin | prevents long lasting LTP by disrupting protein synthesis. |
Anisomycin also | blocks long term retention of a conditioned emotional response when it is injected into the lateral amygdala. |
Protein synthesis is necessary for | long-lasting LTP |