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Handbook Chapter 1

Why is bacterial contamination of platelets of special concern? because this component is stored at room temperature (20-24 degrees C)
The most common bacteria species isolated in platelet products coagulase negative Staphylococcus, Streptococcus species, Staphylococcus aureus and E. coli
Volume RBCs in apheresis platelets less than 2 ml
Volume of RBCs in random donor platelet 0.5 ml
Can ABO incompatible platelets be issued? yes
Immune refractoriness in platelets is most commonly associated with these antibodies antibodies to HLA antigens; rarely, with antibodies to platelet specific antigens
What is the blood product "Thawed plasma?" FFP or FP24 which has been thawed for 24 hours. It can be stored refrigerated for up to 4 additional days.
The most frequent cause of transfusion related fatalities TRALI (Transfusion related acute lung injury); TACO is #2
Cryoprecipitated AHF is a concentrated source of these proteins Factor VIII, vWF, fibrinogen, fibronectin, and Factor XIII
The main source of concentrated fibrinogen in the US for the treatment of patients with acquired deficiency cryo
This blood product is beneficial in bleeding tendency associated with uremia cryo
True or false: Cryoprecipitate must be type specific false
QC requirements for leukoreduced RBCs <5 x 10(6) WBCs and must retain 85% of original RBCs
Leukoreduction decreases the risk of these 3 things 1. FNHTR 2. CMV 3. HLA alloimmuniztion
does leukoreduction mitigate TRALI risk? No
The minimum radiation dose for a blood component is 25Gy at center; 15 Gy at any point in the bag
Which one does not need to be irradiated: A. RBCs B. apheresis platelets C. FFP C. FFP ( also cryo) because acellular
Why would you irradiate a blood product? to prevent Graft versus host disease (GVHD)
Washing is associated with __% loss of RBCs 20%
Washing is associated with __% loss of platelets 33%
Created by: jfshikle
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