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Autonimic Nerv
USCSOM: ANS Physiology
| Question | Answer |
|---|---|
| What is the neurotransmitter associated with parasympathetics? | acetylcholine |
| What type of receptors are associated with parasympathetics? | muscarnic and nicotinic receptors |
| What neurotransmitter is associated with sympathetics? | norepinephrine |
| What receptors are associated with sympathetics? | alpha/beta adrenergic receptors |
| Preganglionic sympathetics release what neuro transmitter? | acetylcholine |
| Cholinergic neurotransmission is found in what type of fibers? | preganglionic para/symp, post para, pstsym sweat |
| What enzyme is involved in the formation of acetylcholine? | choline acetyltransferase |
| What is the primary enzyme that terminates ACH signal? | acetylcholine esterase |
| What are the two types of cholinergic receptors? | nicotinic, muscarinic |
| Ligand-gated ion channels are also known as ______ receptors | nicotinic |
| G-protein coupled receptors are also known as _____ receptors | muscarinic |
| What type of receptors hyperpolarize cardiac myocytes and open K channels? | M2 muscarinic |
| What type of muscarinic receptors increase Ca in neuronal cells? | M1 |
| What type of muscarinic receptors increase exocrine gland secretion? | M3 |
| What muscarinic receptor is associated with nitric osxide induced vasodilation?" | M3 |
| What kind of fibers are most postganglionic neurons? | noradrenergic neurons |
| What neurotransmitter is associated with adrenergic neurons? | norepinephrine |
| What are the catecholamines? | NE, Epi, DA |
| What is the rate limiting step in synthesis of catecholamines? | tyrosine hydroxylase |
| What adernergic receptors down regulate NE release? | alpha-2 receptors |
| What is the major route of inactivation for adrenergic neurotransmission? | reuptake |
| what are the metabolic inactivating enzymes of adrenergic neurotransmission? | MAO (monoamine oxidase) |
| Norepinephrine are agonists to what kind of adrenergic receptors? | a-1, b-1, a-2 |
| Epinephrine is an agonist to what kind of adrenergic receptors? | a-1, b-1, b-2, a-2 |
| What are the major effects of a-1 activation? | vascular, radial mm eye, vas deferens, prostate |
| What are the major effects of b-1 activation? | All cardiac functions |
| What are the effects of b-2 activations? | relax smooth mm |
Created by:
jlellerm
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