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Hematology 1
Hematology in Practice - Chapter 10
| Question | Answer |
|---|---|
| A typical blood picture in infectious mononucleosis is an absolute: | Lymphocytosis without anemia and many reactive lymphocytes |
| A patient who presents with a low white cell count, thrombocytopenia, elevated liver enzymes, and mulberry-like inclusions in the granulocytes is most likely suffering from: | Human ehrlichiosis |
| Which of the following statements is common to most lipid storage diseases? | They are caused by a missing metabolic enzyme. |
| What is an unusual complication that may occur in infectious mononucleosis? | Hemolytic anemia |
| A patient who has a persist leukocytosis, Dohle bodies, and an elevated LAP score most likely has a: | Leukemoid reaction |
| What pools of leukocytes are included in the typical white blood count? | only cells freely circulating |
| What pools of cells is the first to arrive when extra granulocytes are needed in the tissues? Those: | that are marginating. |
| What is the earliest identifiable cell in the granulocyte maturation sequence? | myeloblast |
| What is the earliest stage of maturation where a neutrophil can be distinguished from an eosinophil? | myelocyte |
| What neutrophils are capable of chemotaxis? | band |
| A segmented neutrophil performs all of the following: | chemotaxis, phagocytosis, and pinocytosis |
| A segmented neutrophil can NOT perform: | mitosis |
| What cells are described as a large cell with abundant cytoplasm containing minute granules, lacy chromatin, and an indented or curved nucleus? | Monocyte |
| Which cells are normally produced in multiple sites including the bone marrow, and thymus? | Lymphocytes |
| B cells and T cells are subgroups of what cell type? | Lymphocytes |
| Lymphocytes become transformed when they are: | being stimulated by an antigen. |
| An autosomal disorder that manifests itself with large lysosomal inclusions, recurring infections, and albinism: | Chediak-Higashi |
| Pelger-Huet anomaly is characterized mainly by: | Hyposegmentation of the nucleus is the neutrophils |
| Dohle bodies consist of: | Ribosomal RNA |
| All of the following are lipid storage syndromes/diseases: | Gaucher's disease, Tay-Sachs disease, and Niemann-Pick disease |
| This is not a lipid storage syndrome/disease: | Chediak-Higashi syndrome |
| What inclusions are more likely seen only in the bone marrow? | Morulae from Ehrlichia infections |
| In what condition are monocytes increased? | Tuberculosis |
| What is the causative agent in infectious mononucleosis? | EBV |
| The process of ingesting, digesting, and killing bacteria is termed: | Phagocytosis |
| Qualitative changes in the white blood cell include all of the following: | Toxic granulation, toxic vacuolization, and dohle bodies |
| Qualitative changes in the white blood cell does NOT include: | Gaucher's cells |
| A 17 year-old boy is admitted to the hospital for a fever of unknown origin. His WBC is 20.0 x 10^9/L. All of the following can be seen on his peripheral smear: | toxic granulation, increased band neutrophils, dohle bodies DO NOT see: reactive monocytes |
| Opsonization of neutrophils is defined as: | preparing neutrophils to be ingested |
| All of the following are mechanisms by which neutropenia is usually produced: | decreased production by the bone marrow, impaired release from the bone marrow to the blood, and increased destruction |
| The mechanism by which neutropenia is NOT usually produced: | bacterial infection |