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WVSOM -- Physio

WVSOM -- Hemodynamic principles

Arteries -- large to small Aorta > Muscular Conduit Artery > Arteriole > Capillary
Veins -- to large venule < vein < vena cava
Systolic contraction
diastolic rest
mean pressure diastolic + 1/3(systolic-diastolic)
Compliance ability to stretch and distend with pressure
Transmural pressure difference between the pressure inside teh vessel and the pressure outside the vessel. net pressure is pushing against the wall
capacitance volume contained for a specific pressure
Blood flow to organs altered by controlling vascular smooth muscle tone by local and systemic
Systemic ways to control smooth muscle tone SNS and Hormones
Local ways to control vascular smooth muscle tone metabolic factors and paracrine agents
Blood volume is distributed roughly in accordance with ___________. Metabolic rate
How does gravity affect blood pressure Blood pressure increases the farther it moves away from the heart
Majority of blood is held in the systemic veins
Pressure force per unit area
flow volume transferred per unit time
resistance opposition to flow
Relationship of blood flow to the driving pressure and vascular resistance blood flow is proportional to the pressure difference and inversely proportional to resistance
Cardiac Output Q = (p1-p2)/r
Resistance in Series R1+ R2 + R3 = Rtotal
Resistance in Parallel 1/R + 1/R + 1/R = 1/Rtotal
Main site of resistance in the systemic circulation Arterioles
Bernoulli Principle increase in velocity occurs simutaneoulsy with the decrease in pressure
Hematocrit's effect on viscocity increases it
Laminar blood flow smooth parallel streamlines that slip past each other
Shear stress caused by velocity thru the vessel Generated by the axial streaming of blood cells pushing and shearing them orienting them in one direction
Shear stress effect on vascular wall can activate endothelial factors (NO). Lots of stress can cause damage on the vessel wall and cause an aneurysm
Reynolds Number > 2300 causes turbulence
Turbulence promoted by high velocity, vessel diameter and blood viscosity
Vessel with greatest compliance Veins
why is mean pressure close to diastolic pressure? heart spends longer relaxed than it does in contraction
Right side of heart pumps to Lungs
Left side of heart pumps to systemic circulation
2 organs that receive more blood flow than is required to satisfy metabolic demands skin and kidneys
Blood Flow is directly proportional to pressure gradient
Blow flow is inversely proportional to vascular resistance
Why are capallaries low in overall resistance they are numerous and arranged in parallel
Bernoulli Principle and PE to KE blood potential energy to kinetic energy occurs when cross-sectional area decreases.
Highest blood velocity in laminar blood flow center of the vessel
Created by: tjamrose



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