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Immunologic Disorder

OT Immunologic disorder

Immunologic Disorders123456
Cellular immunity T cells or lymphocytes Helper induce T cell, cytotoxic or killer t cell, supressor t cell, supressor inducer t cell (blank) (blank) (blank) (blank)
Humoral immunity B cells or lymphocytes IgM, IgA,IgG, IgE, IgD (blank) (blank) (blank) (blank)
Tests for cellular immunity Quantitative ( lymphocyte count, T cell subset (CD4, CD8), NK cell numbers) Qualitative (DTH skin test, ability to elaborate cytokines ( IL1,2,4, TNF) Ability to generate MHC-restrict CTL (blank) (blank) (blank)
Tests for humoral immune response serum immunoglobulin levels determination of isohemagglutinin and febrile agglutinin titers determination of antibody titers following immunization with tetanus toxoids, diphtheria toxoid, or pneumococcal polysaccharide vaccines protein electrophoreisis( albumin,globulin,fibrinogen) immunoelectrophoreisis (blank)
Disorders of immunoglobulin overproduction MGUS multiple myeloma waldenstrom macroglobulinemia Amyloidosis heavy chain disease (blank)
Primary Immunologic Difficiency Disorder selective IgA deficiency Bruton's X linked, Degeorge thymic hypoplasia chronic mucocutaneous candidiasis Wiskott-aldrich syndrome chronic granulomatous disease (inability tto develope neutrophils ataxia and aids
Secondary Immunologic Difficiency Disorders AIDS iatrogenic ( cancer chemotherapy) immunodificiency associated with Sarcoidosis and Hodgkins (blank) (blank) (blank)
Cell mediated autoimmunity SLE (blank) (blank) (blank) (blank) (blank)
Antibody-mediated autoimmunity hemolytic anemia idiopathic thrombocytopenia goodpasture's syndrom grave's disease myasthenia gravis type 1 DM
Immune complex disease SLE rhumatoid arthritis drug induced hemolytic anemia drug induced thrombocytopenia (blank) (blank)
Diagnosis agglutination of antigen-coated RBC Enzyme-linked immunoassays (ELISA) immunoflourescence microscopy complement fixation (blank) (blank)
Treatment supression of autoantibody productions (corticosteroids, cytotoxic agents) relieve tissue damage from immune complexes (ASA,NSAID,colchine, corticosteroids) remove offending autoantibodies and circulating immunecomplexes (cytotoxic drugs) (blank) (blank) (blank)
Created by: natkat