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Surgical Pharmacolog
| Term | Definition |
|---|---|
| Absorption | the process by which a drug is taken into the body and moves from the site of administration into the blood. |
| Adverse effect | are undesired, potentially harmful side effects of drugs. |
| agonist | are drugs that bind to or have an affinity (attraction) for a receptor and cause a particular response |
| antagonist | Drugs that bind to a receptor and prevent a response |
| bioavailability | indicates the degree to which the drug molecule reaches the site of action to exert its effects. |
| biotechnology | the concepts of genetic engineering and recombinant DNA technology. |
| biotransformation | In the liver, the chemical composition of a drug is changed by |
| bolus | fast inffusion of medication |
| contraindication | reasons against giving a particular drug |
| distribution | Drug molecules eventually diffuse out of the blood-stream to the site of action i |
| duration | The time between onset and disappearance of drug effects |
| emulsion | in which the medication is contained in a mixture of water and oil bound together with an emulsifier. |
| enteral | indicates that the medication is taken into the gastrointestinal tract, primarily by mouth (orally). |
| excretion | Medications taken into the body are eliminated in the process called |
| hypersensitivity | is an adverse effect resulting from previous exposure to the drug or a similar drug. |
| idiosyncratic effect | rare and unpredictable adverse reactions to drugs. Most idiosyncratic drug reactions are thought to occur in people with some genetic abnormality, causing either an excessive or an inadequate response to a drug. |
| indication | The reason or purpose for giving a medica- tion |
| local effect | work at the site of application |
| onset | The time between administration of a drug and the first appearance of effects is |
| parenteral | any route other than the digestive tract, the most common of which are subcutaneous, intramuscular, and intravenous |
| pharmacodynamics | examines how the action of the drug affects the body. |
| pharmacokinetics | focuses on how the body processes drugs, |
| plasma protein binding | drug molecules bind to proteins (albumins and globulins) contained in plasma—the liquid portion of blood— |
| reconstituted | to form a solution that can be administered by injection |
| side effect | predictable but unintended effect of a drug. Side effects are rarely serious,but usually unavoidable. |
| solubility | its ability to be dissolved |
| solution | is a mixture of drug particles (called the sol-ute) fully dissolved in a liquid medium (called the solvent such as water or saline). |
| suspension | a form in which solid undissolved particles float (are sus- pended) in a liquid. |
| synergist | A drug that enhances the effect of another drug is |
| systemic effect | throughout the entire body |
| topical | are applied to the skin surface or a mucous membrane–lined cavity |
| controlled substances | something you can become addicted to and that is controlled by the law |
| narcotics | natural opioid drugs |
| DEA | Drug Enforcement Administration: of the Department of Justice was established to enforce the Controlled Substances Act |
| FDA | Federal Drug Administration: inspects the facilities where drugs are made, reviews new drug applications,investigates and removes unsafe drugs from the market,and requires proper labeling of drugs. |
| The Joint Comission | evaluates and accredits approximately 16,000 health care organizations and programs in the United States. |
| OTC | over-the-counter category of medications that did not require a prescription |
| PDR | Physicians’ Desk Reference, or PDR. It provides easy access to information on several thousand medications used in medical and surgical practice. |
| USP-NF | UNITED STATES PHARMACOPEIA AND NATIONAL FORMULARY |