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Phys Spring 4 Lec 2

Pituitary Hormones & Hypothalamic Control Part I

What does the anterior pituitary produce? GH, ACTH, TSH, FSH & LH, PRL (prolacin)
What does the posterior pituitary produce? ADH, oxytocin
What sort of information does the hypothalamus receive? 1. Internal homeostasis (water levels, electrolytes, etc), 2. limbic system responses (stress, fear, strong emotion), 3. circadian rhythms, 4. olfactory sensations
Which hormones does the hypothalamus release onto the anterior pituitary? Releasing hormones - stimulatory or inhibitory
What is the action of GH? Stimulates body growth, lipid & CHO metabolism
What is the action of ACTH? Glucocorticoid from the adrenal cortex
What is the action of TSH? Production of thyroid hormones, maintenance of thyroid cell size
What is the action of FSH? Ovarian follicles and spermatogenesis
What is the action of LH? Steroidogenic effect on gonads
What is the action of PRL? Stimulates milk production
Discuss the hypothalamic-hypophyseal portal system The artery --> base of pituitary breaks up into capillaries, receives releasing hormones from hypothalamus, forms into small veins, then breaks up again into capillaries in the anterior lobe
Discuss hypothalamic neurons in the pituitary gland Anterior lobe: neurons end on blood vessels; Posterior lobe: neuron endings for the posterior lobe
Discuss releasing hormones Formed in hypothalamic neurons, released like NT from axon terminals. Some are stimulatory, some are inhibitory
What are the (4) stimulating releasing hormones from the hypothalamus? 1. TRH (stimulates TSH); 2. GnRH (stimulates FSH & LH); 3. CRH (Stimulates ACTH); 4. GHRH (stimulates GH) - all small peptides
What are the (3)inhibitory releasing hormones from the hypothalamus? 1. Somatostatin (inhibits GH) - a small peptide; 2. Dopamine/PIH (prolactin-inhibiting hormone); 3. GnIH - Gonadotropic inhibitory hormone
Created by: hclark86