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Mech of Solute Trans

WVSOM Class of 2012 Mechanisms of Solute Transport

how does prilosec work? inhibits membrane transport process
what are three examples of cell function? homeostasis: moving H+ ions out of cell; metabolism: allowing glucose into cell; signaling: allowing calcium ions into cell
what substances are not likely to cross the cell membrane? cellular proteins
what two ways can molecules move? diffusion and bulk flow
what does bulk flow require to move molecules? driving pressure
molecules cross membranes by what two methods? simple or facilitated diffusion
are ion channels an example of simple or facilitated diffusion? facilitated
do molecules move up or down their concentration gradient? down
rate of diffusion depends on what factors? concentration difference, area available, lipid solubility
lipid solubility depends on what factors? size and charge (small and uncharged more soluble)
what does fick's law state? rate of diffusion is proportional to concentration of c1-c2
what is the formula for fick's law? J=PA(C1-C2) P is permeability coefficient, A is Area, C1 is area of high concentration, C2 is area of low concentration
facilitated diffusion is saturable. what does that mean? there are a limited number of transport proteins that are available
channels control permeability to ions through what mechanisms? gates and selective permeability
what two ways can channels control ion gates? transmitter binding and voltage change
what mechanism moves substances from areas of low concentration to high concentration? active transport
how is the energy in active transport made? hydrolysis of ATP
what maintains Na+ concentration gradient? Na+/K+ ATPase
what is the ration of sodium ions to potassium ions in active transport? 3:2
secondary active transport uses what method? co-transport
what is the term for when a molecule is co-transporedt into the cell? symport
what is the term for when a molecule is co-transported out of the cell? antiport
in parietal cell, what mechanisms are occuring? carbonic acid dissociates into hydrogen and bicarbonate; hydrogen exchanges with potassium; bicarbonate goes into blood in exchange for chloride; hydrogen and chloride together are pumped into the stomach
what makes carbonic acid? carbonic anhydride
how does omeprazole work? inhibits the hydrogen/potassium ATPase pump
Created by: mhassan



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