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Mech of Solute Trans
WVSOM Class of 2012 Mechanisms of Solute Transport
| Question | Answer |
|---|---|
| how does prilosec work? | inhibits membrane transport process |
| what are three examples of cell function? | homeostasis: moving H+ ions out of cell; metabolism: allowing glucose into cell; signaling: allowing calcium ions into cell |
| what substances are not likely to cross the cell membrane? | cellular proteins |
| what two ways can molecules move? | diffusion and bulk flow |
| what does bulk flow require to move molecules? | driving pressure |
| molecules cross membranes by what two methods? | simple or facilitated diffusion |
| are ion channels an example of simple or facilitated diffusion? | facilitated |
| do molecules move up or down their concentration gradient? | down |
| rate of diffusion depends on what factors? | concentration difference, area available, lipid solubility |
| lipid solubility depends on what factors? | size and charge (small and uncharged more soluble) |
| what does fick's law state? | rate of diffusion is proportional to concentration of c1-c2 |
| what is the formula for fick's law? | J=PA(C1-C2) P is permeability coefficient, A is Area, C1 is area of high concentration, C2 is area of low concentration |
| facilitated diffusion is saturable. what does that mean? | there are a limited number of transport proteins that are available |
| channels control permeability to ions through what mechanisms? | gates and selective permeability |
| what two ways can channels control ion gates? | transmitter binding and voltage change |
| what mechanism moves substances from areas of low concentration to high concentration? | active transport |
| how is the energy in active transport made? | hydrolysis of ATP |
| what maintains Na+ concentration gradient? | Na+/K+ ATPase |
| what is the ration of sodium ions to potassium ions in active transport? | 3:2 |
| secondary active transport uses what method? | co-transport |
| what is the term for when a molecule is co-transporedt into the cell? | symport |
| what is the term for when a molecule is co-transported out of the cell? | antiport |
| in parietal cell, what mechanisms are occuring? | carbonic acid dissociates into hydrogen and bicarbonate; hydrogen exchanges with potassium; bicarbonate goes into blood in exchange for chloride; hydrogen and chloride together are pumped into the stomach |
| what makes carbonic acid? | carbonic anhydride |
| how does omeprazole work? | inhibits the hydrogen/potassium ATPase pump |