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AP in Cardiac Muscle

AP in cardiac muscle cells

Step 1 - Rapid Depolarization Threshold. Voltage gated Na channels opne and membrane becomes more permeable to Na. Massive influx of Na and rapid DP of sarcolemma. Channels = Fasr Channels b/c they are only open for a few miliseconds
Step 2 - Plateau transmembrane potential = +30 mv. Voltage regulated Na channels close. Cell pumps out Na out. Slow Ca channels opening. (175 msec open for) Ca enters the sarcoplasm (balances loss of + ions) 0 mv.
Step 3 - Repolarization Slow channels keep closing. Slow K channels closing. K ions rush out of cell rapidl, repolarization restores resting potential.
Created by: zeenat