Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Physio Ch. 5

ligans bind to...and are ususally..such as... receptors...chemical messengers...hormones, neurots and paracrine/autocrine agents
paracrine/autocrine agent examples histamine and nitric oxide
chemical messengers NEED...which are generally... receptors...proteins or glycoprotein with a chemical specific binding site
receptors have...so it only binds to a... specificity...specific ligand
receptors are located in the... cell plasma membrane (transmembrane protien)
cell membranes allow lipid insoluble messengers to enter the cell
receptors can also be located inside the cell or nucleus
characteristics of messenger-receptor interactions affinity, % saturation, and competition
competition involves agonists (promote activity) and antagonists (block activity)
regulation of receptors is either down or up regulation
down regulation decreases or decreases in the affinity of the receptor
down regulation involves... negative feedback mechanism
neg. feedback mechanisms for regulatin receptors increases the... amt of ligand > ^ messenger - receptor interaction
^ amt of ligand > ^ messenger - receptor interaction increases...and involves the...which lastly... amt of desired action...internalization of receptors (endocytosis) > ^ breakdown of receptors...decreases amount of reaction
negative example of down-regulation would be insulin resistance and dec insulin receptor sensitivity
insulin resistance and dec insulin receptor sensitivity results in dec glucose transporters in skeletal muscle and adipose tissue
up-regulation involves the addition of receptors to cell plasma membrane or increase in the affinity of the receptor (exocytosis)
signal transduction pathways cause the...and involves the steps from.. domino effect...signal to desired response
signal transduction pathways involve receptor activation and transduction
receptor activation involves messenger-recepter interaction
transuction involves...and may also involve... transformation of a signal to a response...many steps and many chemicals/reactions
lipid soluble messengers in signal transduction pathways: the receptors are...and thelipid-soluble messengers can... intracellular...pass through the phospholipid bilayer
lipid soluble messengers that can pass through the phospholipid bilayer include steriod hormones, thyroid hormones, and 1,25 hydroxyvitamin D (steroid derivative)
most lipid soluble messengers alter...because the...act as a... rates of DNA transcription...receptor and bound messenger...transcription factor
lipid-soluble messengers may increase or decrease gene activity
plasma membrane receptors for...and their mechanism of transduction includes... lipid soluble messengers...ion channels, enzymes, activate JAK kinases, activate G proteins
the plasma membrane receptors for lipid soluble messengers: ion channels are chemically ligand gated channels
the plasma membrane receptors for lipid soluble messengers: enzymes are usually...and some receptors...or they... kinases that phosphorylate a protein...act as enzymes...activate ligand protein as an ezymes
the plasma membrane receptors for lipid soluble messengers: activating JAK kinases, jak stands for...and the receptor is not the...but it activates... just another kinase...kinase...a seperate kinase and they you transfer energy to another molecule
the plasma membrane receptors for lipid soluble messengers: activating G proteins, G protein complexes are in the...and the change in G proteins activates... membrane...an additional protein
G proteins may result in...or in... change in membrane potential (get a response)...generation of a second messenger (get a response)
Created by: handrzej