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Chap12 Leuko DelTech

Chapter 12 review on Leukopoiesis DelTech Owens

What is the development of white blood cells called? Leukopoiesis
Where does leukopoiesis occur? The medullary cavity (bone marrow). Some lymphocytes develop in the thymus (T cells)
What is another word for white blood cells? Leukocyte
How are leukocytes categorized? By 1) specific function 2) site of origin 3) morphology
What are the 2 basic types of leukocytes? Granular and agranular
Which series of leukocytes has granules in it? (Granular) Myelocytic series
Which series of leukocytes has no granules in it? (Agranular) Lymphocytes and monocytes
Where are the 4 locations for granulocytes in the body? 1) bone marrow 2) circulating blood 3) marginal pool/endothelial lining 4) tissues
What is the first stage of a granulocyte's development? Myeloblast
What is the 2nd stage of a granulocyte's development? Promyelocyte
What is the 3rd stage of a granulocyte's development? Neutrophil Myelocyte
What is the 4th stage of a granulocyte's development? Neutrophilic Metamyelocyte
What is the 5th stage of a granulocyte's development? Neutrophilic Band
What is the 6th stage of a granulocyte's development? Neutrophilic Segment
What is the primary function of a neutrophilic segment cell? Phagocytosis
What are the 3 stages of phagocytosis? 1) migration and diapedsis 2) opsonization and recognition 3)phagocytosis, killing and digestion
__ is the movement of the seg through the vessel wall. Diapedesis
Directional migration to the site of an injury is called __. Chemotaxis
Opsonization is the mechanism of __ and attachment to the organisms to be ingested during phagocytosis. recognition
After a bacteria is coated in immunoglobulins and complements, it is referred to as __. opsonin
When a neutrophil attacks an invader, its cytoplasm forms a __ that surrounds the microorganism. pseudopod
After a neutrophil has formed a pseudopod around an invading microorganism, the resulting vacuole is called a __. phagosome
Once a neutrophil has enveloped an invading microorganism, its cytoplasmic __ migrate to the phagosome/vacuole. granules
A __ has red-eosin secondary granules. eosinophil
A __ has large, deep purple to black granules. basophil
__ cells are really just basophils in tissue. Mast
Monocytes and macrophages are __. (With or without granules?) agranular
The first stage of the monocytic/macrophage line is a __. monoblast
The 2nd stage of the monocytic/macrophage line is a __. promonocyte
The 3rd stage of the monocytic/macrophage line is a __. monocyte
The 4th stage of the monocytic/macrophage line is a __. macrophage
Monoblasts are usually seen in the __ __. bone marrow
Monoblasts can also be found in the __. spleen
True or false: Monoblasts are granular white blood cells? False
Promonocytes are the same size as a __. monoblast
__ destroy old red blood cells. monocytes
Monocytes migrate into tissue to become __. macrophages
Macrophages are basically __ in the tissue. monocytes
__ are anti-tumor cells. macrophages
Lymphocytes develop in what 4 places? 1) bone marrow 2) lymphatic system 3) spleen 4) thymus
Lymphocytes can live from __ to __ years. five to ten years
Lymphocytes that live 5 to 10 years are called __ cells. memory
Most white blood cells only live __ to __ days. seven to ten days
The thymus develops __ cells. T cells
__ __ develops B cells. Bone marrow
Once cells develop into T or B cells, they go to the secondary lymphatic tissues, which are what 4 areas? 1) spleen 2) tonsils 3) lymph nodes 4) cells that respond to specific antigens
Reactive lymphocytes have a __ __ appearance. fried egg
The first stage of lymphocytic cell maturation is called a __. lymphoblast
The 2nd stage of lymphocytic cell maturation is called a __. prolymphocyte
The 3rd stage of lymphocytic cell maturation is called a __. mature lymphocyte
A lymphoblast has a __ cytoplasm. blue
a prolymphocyte has a __ __ cytoplasm. light blue
B cells transform into __ cells for antibody protection. plasma
Receptors or markers that come and go depending on development and need are called __ __. T cells
CD4 T cells are also called __ __. helper cells
CD8 T cells are also called __ __. suppressor cells
Lymphoctyes are __ of the immune system. regulators
Once a lymphocyte is activated to fight foreign objects, it becomes a __ lymphocyte. reactive
WBCs that are granulitic usually end with the suffix __. phil
WBCs that are agranulitic usually end with the suffix __. cyte
Lymphocytes are classified by __ __. flow cytometry
CD stands for __ __ __. cluster of differentiation
What are lymphocytes classified for? lymphotytic leukemias and lymphomas
Lymphoblasts in the circulating blood are only seen in patients with __. leukemia
Plasma cells have a __ __ cytoplasm with a pale area near the nucleus. dark blue
If the immune system doesn't react quickly enough to an invader, macrophages release __. IL-1
If the immune system doesn't react quickly enough to an invader, T cells release factors that increase development of antigen specific _ __ and __ T cells. B lymphs and cytotoxic T cells
BCDF stands for __. B Cell Differentiation Factor
B cells with the help of IL-1 and BCDFs promote differentiating into __ __. plasma cells
Plasma cells start production of __ in fighting off invaders. immunoglobulins
A foreign object in the body that produces an immune response is called an __. antigen
Lymphocytes, once activated, change into __ __ to fight off antigens. reactive lymphocytes
Created by: IsaacJ
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