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Chap12 Leuko DelTech
Chapter 12 review on Leukopoiesis DelTech Owens
| Question | Answer |
|---|---|
| What is the development of white blood cells called? | Leukopoiesis |
| Where does leukopoiesis occur? | The medullary cavity (bone marrow). Some lymphocytes develop in the thymus (T cells) |
| What is another word for white blood cells? | Leukocyte |
| How are leukocytes categorized? | By 1) specific function 2) site of origin 3) morphology |
| What are the 2 basic types of leukocytes? | Granular and agranular |
| Which series of leukocytes has granules in it? (Granular) | Myelocytic series |
| Which series of leukocytes has no granules in it? (Agranular) | Lymphocytes and monocytes |
| Where are the 4 locations for granulocytes in the body? | 1) bone marrow 2) circulating blood 3) marginal pool/endothelial lining 4) tissues |
| What is the first stage of a granulocyte's development? | Myeloblast |
| What is the 2nd stage of a granulocyte's development? | Promyelocyte |
| What is the 3rd stage of a granulocyte's development? | Neutrophil Myelocyte |
| What is the 4th stage of a granulocyte's development? | Neutrophilic Metamyelocyte |
| What is the 5th stage of a granulocyte's development? | Neutrophilic Band |
| What is the 6th stage of a granulocyte's development? | Neutrophilic Segment |
| What is the primary function of a neutrophilic segment cell? | Phagocytosis |
| What are the 3 stages of phagocytosis? | 1) migration and diapedsis 2) opsonization and recognition 3)phagocytosis, killing and digestion |
| __ is the movement of the seg through the vessel wall. | Diapedesis |
| Directional migration to the site of an injury is called __. | Chemotaxis |
| Opsonization is the mechanism of __ and attachment to the organisms to be ingested during phagocytosis. | recognition |
| After a bacteria is coated in immunoglobulins and complements, it is referred to as __. | opsonin |
| When a neutrophil attacks an invader, its cytoplasm forms a __ that surrounds the microorganism. | pseudopod |
| After a neutrophil has formed a pseudopod around an invading microorganism, the resulting vacuole is called a __. | phagosome |
| Once a neutrophil has enveloped an invading microorganism, its cytoplasmic __ migrate to the phagosome/vacuole. | granules |
| A __ has red-eosin secondary granules. | eosinophil |
| A __ has large, deep purple to black granules. | basophil |
| __ cells are really just basophils in tissue. | Mast |
| Monocytes and macrophages are __. (With or without granules?) | agranular |
| The first stage of the monocytic/macrophage line is a __. | monoblast |
| The 2nd stage of the monocytic/macrophage line is a __. | promonocyte |
| The 3rd stage of the monocytic/macrophage line is a __. | monocyte |
| The 4th stage of the monocytic/macrophage line is a __. | macrophage |
| Monoblasts are usually seen in the __ __. | bone marrow |
| Monoblasts can also be found in the __. | spleen |
| True or false: Monoblasts are granular white blood cells? | False |
| Promonocytes are the same size as a __. | monoblast |
| __ destroy old red blood cells. | monocytes |
| Monocytes migrate into tissue to become __. | macrophages |
| Macrophages are basically __ in the tissue. | monocytes |
| __ are anti-tumor cells. | macrophages |
| Lymphocytes develop in what 4 places? | 1) bone marrow 2) lymphatic system 3) spleen 4) thymus |
| Lymphocytes can live from __ to __ years. | five to ten years |
| Lymphocytes that live 5 to 10 years are called __ cells. | memory |
| Most white blood cells only live __ to __ days. | seven to ten days |
| The thymus develops __ cells. | T cells |
| __ __ develops B cells. | Bone marrow |
| Once cells develop into T or B cells, they go to the secondary lymphatic tissues, which are what 4 areas? | 1) spleen 2) tonsils 3) lymph nodes 4) cells that respond to specific antigens |
| Reactive lymphocytes have a __ __ appearance. | fried egg |
| The first stage of lymphocytic cell maturation is called a __. | lymphoblast |
| The 2nd stage of lymphocytic cell maturation is called a __. | prolymphocyte |
| The 3rd stage of lymphocytic cell maturation is called a __. | mature lymphocyte |
| A lymphoblast has a __ cytoplasm. | blue |
| a prolymphocyte has a __ __ cytoplasm. | light blue |
| B cells transform into __ cells for antibody protection. | plasma |
| Receptors or markers that come and go depending on development and need are called __ __. | T cells |
| CD4 T cells are also called __ __. | helper cells |
| CD8 T cells are also called __ __. | suppressor cells |
| Lymphoctyes are __ of the immune system. | regulators |
| Once a lymphocyte is activated to fight foreign objects, it becomes a __ lymphocyte. | reactive |
| WBCs that are granulitic usually end with the suffix __. | phil |
| WBCs that are agranulitic usually end with the suffix __. | cyte |
| Lymphocytes are classified by __ __. | flow cytometry |
| CD stands for __ __ __. | cluster of differentiation |
| What are lymphocytes classified for? | lymphotytic leukemias and lymphomas |
| Lymphoblasts in the circulating blood are only seen in patients with __. | leukemia |
| Plasma cells have a __ __ cytoplasm with a pale area near the nucleus. | dark blue |
| If the immune system doesn't react quickly enough to an invader, macrophages release __. | IL-1 |
| If the immune system doesn't react quickly enough to an invader, T cells release factors that increase development of antigen specific _ __ and __ T cells. | B lymphs and cytotoxic T cells |
| BCDF stands for __. | B Cell Differentiation Factor |
| B cells with the help of IL-1 and BCDFs promote differentiating into __ __. | plasma cells |
| Plasma cells start production of __ in fighting off invaders. | immunoglobulins |
| A foreign object in the body that produces an immune response is called an __. | antigen |
| Lymphocytes, once activated, change into __ __ to fight off antigens. | reactive lymphocytes |
Created by:
IsaacJ
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