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Gas Transport

Hemoglobin

QuestionAnswer
How much O2 does Plasma transport? <2%
How much O2 does Hemoglobin transport? 98%
How many O2 molecules can Hemoglobin carry and at what % saturation? 4 @ 100% saturation = Oxyhemoglobin
How much O2 is unloaded at the tissues? 20%
How does LOW PO2 effect HgbO2 dissociation? Lower PO2 --> LESS O2 affinity (INCREASE release of O2)
How does a HIGH pH effect HgbO2 dissociation? HIGIH acidity --> LESS O2 affinity --> (INCREASE release of O2)
How does a LOW pH effect HgbO2 dissociation? LOW acidity --> HIGHER O2 affinity
How does HIGH Temperature effect HgbO2 dissociation? HIGH Temp. --> LESS O2 affinity (INCREASE release of O2)
How does LOW Temperature effect HgbO2 dissociation? LOW Temp. --> HIGH O2 affinity
What does affinity mean? Hold
Which 2 influences on HgbO2 dissociation effect protein shape? pH, Temp.
How much CO2 is carried in Plasma? CO2 <--dissolved --> <10%
How much CO2 is carried in RBC as Carbamaminohemoglobin? CO2 <-->reduced Hb <--> HbCO2 (30%)
How much CO2 is carried in RBC as Carbonic Acid? CO2 + H2O <--> H2CO3 <--> H+ + HCO3- (60%)
Created by: Kristel