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Gas Transport
Hemoglobin
Question | Answer |
---|---|
How much O2 does Plasma transport? | <2% |
How much O2 does Hemoglobin transport? | 98% |
How many O2 molecules can Hemoglobin carry and at what % saturation? | 4 @ 100% saturation = Oxyhemoglobin |
How much O2 is unloaded at the tissues? | 20% |
How does LOW PO2 effect HgbO2 dissociation? | Lower PO2 --> LESS O2 affinity (INCREASE release of O2) |
How does a HIGH pH effect HgbO2 dissociation? | HIGIH acidity --> LESS O2 affinity --> (INCREASE release of O2) |
How does a LOW pH effect HgbO2 dissociation? | LOW acidity --> HIGHER O2 affinity |
How does HIGH Temperature effect HgbO2 dissociation? | HIGH Temp. --> LESS O2 affinity (INCREASE release of O2) |
How does LOW Temperature effect HgbO2 dissociation? | LOW Temp. --> HIGH O2 affinity |
What does affinity mean? | Hold |
Which 2 influences on HgbO2 dissociation effect protein shape? | pH, Temp. |
How much CO2 is carried in Plasma? | CO2 <--dissolved --> <10% |
How much CO2 is carried in RBC as Carbamaminohemoglobin? | CO2 <-->reduced Hb <--> HbCO2 (30%) |
How much CO2 is carried in RBC as Carbonic Acid? | CO2 + H2O <--> H2CO3 <--> H+ + HCO3- (60%) |