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Hemostasis
Prevention of Blood Loss
Question | Answer |
---|---|
What factors are used to create Hemostasis? | Vascular Spasm, Coagulation, Anti-coagulation |
What is the definition of Vascular spasm? | constriction of Arteirioles when cut |
How are Sympathetic Fibers associated with Vascular Spasm? | Pain --> reflex excitation of Sympathetic Fibers --> Vascular Smooth Muscle |
How is Serotonin associated with Vascular Spasm? | Local release of Serotonin from Platelets causes Vasoconstriction |
What is the definition of Coagulation? | formation of fibrous Protein network which traps Blood Cells creating a Thrombus |
Name 2 Anticoagulants? | Heparin, Coumarin |
What is the function of Heparin? | Thrombin INHIBITOR; released from Basophils and/or Liver & Lungs |
What is the function of Coumarin? | Vitamin K ANTAGONIST |
What are Fibrinolysins? | Clot Busters |
Name a Fibrinolysin and its function. | Plasmin - HYDROLYZES Fibrin; released from Vascular Endothelium as Tissue Plasminogen Activator (tPA) |