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Chemical Immunity

Antibody-Mediated Immunity

What is the definition of Antibody-Mediated Immunity? the production of specific Antibodies in response to invading microbes
What is the 1st step in Antibody-Mediated Immunity? ARRIVAL of microbes in Lymph Organ
What is the 2nd step in Antibody-Mediated Immunity? BINDING of Microbial Antigen to receptors on specific B-cells
What is the 3rd step in Antibody-Mediated Immunity? MITOSIS of a specific B-cell population (clone), programed to produce Opposing Antibodies
What is the 4th step in Antibody-Mediated Immunity? "activated" B-cells are TRANSFORMED into Plasma or Memory cells
What is the function of Plasma Cells? SYNTHESIZE IgM Antibodies 1st, then IgG in 2nd response
What is the function of Memory Cells? remain dormant for years, then quickly divide and become Plasma cells during a 2nd response
What is the significance of Memory cells? save time/life in case of 2nd arrival of microbes
Why do Microbes invade Lymph organs instead of Blood? 1. Lower pressure; 2. Lymph organs are designed to pick up Microbes
When is Antibody-Mediated Immunity activated? after Non-specific Defense is breached
How long does it take for Antibodies to be produced during a 1st exposure? about 28 days
How long does it take for Antibodies to be produced during a 2nd exposure? about 7 days
What is the 5th step in Antibody-Mediated Immunity? Antibodies ATTACH to foreign cells Antigens and "mark" the cells for Phagocytosis by NK-cells or Macrophages
Created by: Kristel