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Non-specific Defense
Defense Mechanisms
Question | Answer |
---|---|
What is the definition of Non-specific Defenses? | those that do not recognize specific foreign cells |
What is the significance of Non-specific Defenses? | reduce burden of Specific Defenses |
What are the Non-specific Defenses? | 1. Skin & Mucus Membranes; 2. Phagocytosis; 3. Inflammatory Response; 4. Fever; 5. Interferons |
What type of defense is provided by Skin and Mucus Membranes? | Physical/Chemical barriers to infection |
What type of defense is provided by Phagocytosis? | Leukocytes (granular & macrophages) throught body organs --> pus |
What is pus? | dead WBC and Bacteria |
What type of defense is provided by Inflammatory Responses? | release of Histamine & Prostaglandins --> Vasodilation/Edema --> slows spread of Infectious Agents --> Improves EXTRAcellular Phagocytosis & enables Antibody diffusion |
What type of defense is provided by Fever? | Interleukin 1 secreted by Macrophages exposed to Pathogenic Bacteria --> denature |
What are Interferons? | Proteins released by Virus infected cells |
How do Interferons protect the body? | enhance activity of NK-cells and stimulate nearby host cells to Synthesize Anti-viral Enzymes |