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Non-specific Defense

Defense Mechanisms

What is the definition of Non-specific Defenses? those that do not recognize specific foreign cells
What is the significance of Non-specific Defenses? reduce burden of Specific Defenses
What are the Non-specific Defenses? 1. Skin & Mucus Membranes; 2. Phagocytosis; 3. Inflammatory Response; 4. Fever; 5. Interferons
What type of defense is provided by Skin and Mucus Membranes? Physical/Chemical barriers to infection
What type of defense is provided by Phagocytosis? Leukocytes (granular & macrophages) throught body organs --> pus
What is pus? dead WBC and Bacteria
What type of defense is provided by Inflammatory Responses? release of Histamine & Prostaglandins --> Vasodilation/Edema --> slows spread of Infectious Agents --> Improves EXTRAcellular Phagocytosis & enables Antibody diffusion
What type of defense is provided by Fever? Interleukin 1 secreted by Macrophages exposed to Pathogenic Bacteria --> denature
What are Interferons? Proteins released by Virus infected cells
How do Interferons protect the body? enhance activity of NK-cells and stimulate nearby host cells to Synthesize Anti-viral Enzymes
Created by: Kristel