Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Hem1 Chp7 Hematopoie
Preparing for test (chapters 7-11&16) in Hematology 1 DelTech Owens
| Question | Answer |
|---|---|
| What do you call the formation of blood cells? | Hematopoiesis |
| How many phases of hematopoiesis are there in our lives? | 3 |
| The 2nd phase of hematopoiesis is called __. | Hepatic phase |
| What 4 organs generate blood cells during the Hepatic phase? | Spleen, thymus, liver, lymph nodes (STLLn, or "Still-in") |
| The 1st phase of hematopoiesis is called __. | Mesoblastic phase (or Yolk Sac Phase) |
| When does the mesoblastic phase begin? | 2-3 weeks after fertilization |
| The mesoblastic phase ends after __ weeks. | 6 |
| During the mesoblastic phase of Hematopoiesis, stem cells from the yolk sac differentiate into primitive __. | Erythroblasts |
| What is an erythroblast? | Primitive pluripotential cells that are precursors of all blood cell lines. |
| What is the first lymphatic organ to develop? (This happens during the hepatic phase) | The thymus |
| Where do B cells develop in the hepatic phase? | The spleen and kidney |
| What phase does production of megakaryocytes begin in? | Hepatic phase |
| What is lymphopoiesis? | The generation of lymphocytes, more formally called lymphoid hematopoiesis. |
| The spleen is almost the sole site of __ during the hepatic phase. | lymphopoiesis |
| What is the 3rd phase of hematopoiesis? | Medullary phase (or myeloid phase) |
| When does the medullary phase begin? | Five months |
| Bone marrow activity increases tremendously during the __ phase. | Medullary phase |
| After __ months, the bone marrow is the primary source of hematopoiesis. | 6 |
| CSF stands for __. | colony stimulating factors |
| What do colony stimulating factors do? | Cause the cells to proliferate and differentiate into specific kinds of blood cells |
| Under hypoxic conditions, the __ will produce and secrete erythropoietin to increase the production of red blood cells. | Kidney |
| What is the most common cause of anemia? | Iron deficiency |
| The kind of bone marrow that produces stem cells and all blood cell lines is called __ __ __. | Red bone marrow |
| Megakaryocytes are __ in size and produce __. | Large in size and produce platelets. |
| Macrophages are __ blood cells. | White |
| What color is the bone marrow of 3 year old? | Entirely red |
| At what age does a child's bone marrow start to turn from red to (partially) yellow? | 4 years of age. The process ends around 7 years of age. |
| Adult red marrow is restricted to -- -- -- -- -- -- --. | Flat bones, sternum, vertebrae, pelvis, ribs, skull, proximal ends of long bones. |
| If the body needs to produce more blood cells than the red bone marrow can provide, it can revert to the __ and has __ __ __ as a reserve. | The spleen, has yellow marrow-fat as a reserve. |
| How long do RBCs live? | 120 days |
| What is the normal percentage rate of loss for RBCs in the body per day? | 2% |
| Granulocytes are __ blood cells characterized by the presence of __ in their cytoplasm. | White blood cells, granules in their cytoplasm |
| Adult bone marrow tissue consists of __% marrow and __% fat. | 50, 50 |
| In a patient with leukemia, the ratio of __ marrow to fat increases dramatically. | red |
| Phagocytic __ cells in the spleen, liver, and other strategic locations "eat" pathogens as well as eliminating debris from the blood. | macrophage |
| The __ is the storage cite for platelets. | spleen |
| Splenomegaly is __? | an enlargement of the spleen |
| What does splenomegaly indicate? | leukemia, lymphomas, RBC problems |
| Where does differentiation of T cells occur? | Thymus |
| As you get older, the thymus __. | Shrinks |
| Lymph nodes are located __ __ in the body. | almost everywhere |
| B cells are created in the __ __. | lymph nodes |
| What are the 3 main functions of lymph nodes? | 1. Form new lymphocytes, 2. process specific antibodies (immunoglobulins), 3. filer debris and bacteria |
| What is the monophylectic theory? | All blood cells are derived from a common stem cell. |
| What is the polyphyletic theory? | There's a separate and distinct stem cell compartment for each blood cell type. |
| Two major types of stem cells are: | noncommitted (also called undifferentiated) and multipotential |
| What kind of cell is responsible for the stimulation or inhibition of blood cells? | cytokine |
| Another word for white blood cells? | Leukocytes |
| What are the 2 main types of white blood cells | myelocytes and lymphocytes |
| What is leukipoietin? | a hypothetical substance presumed to be the humoral means of regulating leukopoiesis. |
| What is thrombopoietin? | A colony-stimulating factor that regulates production of platelets. |
| What kind of cells platelets come from? | Megakaryocytes |
| Where is erythropoietin produced? | The kidney |
Created by:
IsaacJ
Popular Laboratory Science sets