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Toxicology Test

Enter the letter for the matching Answer
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1.
receptor expression repression
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2.
its goal is to provide risk managers with a rational basis for making decisions about managing the use of chemicals or physical gents to protect health and the environment
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3.
hybrid of analytical chemistry and toxicological principles
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4.
specialized areas of environmental toxicology; focuses on impacts of toxic substances on population dynamics in ecosystem
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5.
exam for toxicology is administered by__________ and taken to become _________
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6.
toxic substances produced by or are by-products of anthropogenic activities (man's activity) (exogenous)
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7.
Field that describes gross toxic responses using in vitro and in vivo systems
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8.
2 offices in charge of drug safety in FDA
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9.
specialties (practice areas in toxicology)
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10.
science of determining if drugs and chemicals are safe for use... use information from descriptive and mechanistic toxicity data and epidemiology data (PAPER scientist)
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11.
principles of toxicology
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12.
occurrence of toxic effect is dependent on:
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13.
less of a toxic agent reaching its target
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14.
emerging sub-discipline of toxicology ; contibute to DNA; data from these techniques are descriptive but also provide info on mechanisms
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15.
when two compounds together interfere with each other's effect
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16.
three things importnant in environmental toxicology
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17.
exposure for 1 month or less
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18.
exposure for 1-3 months
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19.
study of adverse effects of chemicals in living organisms
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20.
decreased responsiveness to a toxic effect resulting from prior exposuure to a chemical or strucutrally related compound
A.
office in drug safety ; drug safety oversight board
B.
transport, fate, and interactions
C.
descriptive toxicology
D.
forensics toxicology
E.
subacute
F.
Risk Assessment
G.
antagonism
H.
source, exposure, ADME, Dose, MOA, endpoint(target)
I.
toxicology
J.
Regulatory toxicology
K.
Toxicogenomics
L.
tolerance
M.
dispositional tolerance
N.
reduced responsiveness
O.
toxicant
P.
chemical/physical properties, exposure, metabolized, concentration, susceptibility
Q.
ecotoxicology
R.
subchronic
S.
AACT (american academy of clinical toxicology); DABAT (diplomat of american board of applied toxicology)
T.
food, analytical/forensic, clinical, occupational, regulatory, environmental
Type the Answer that corresponds to the displayed Question.
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21.
compound found in an organism but not normally produced by or expected to be present in that organism
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22.
they work to set levels for safe exposures to: environmental contaminants, food additives, medicinals
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23.
when combined effect is much greater than the sum of the effects of each given alone
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24.
data from these studies used for safety eval. for human health and environmental risk assessments, provides a starting point for elucidating mechanisms
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25.
Field that identifies and understands cellular, biochemical, and molecular mechanisms causing toxic effects (work in labs ; work at the bench)
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agent that can cause a deleterious response in a biological system
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toxic substances produced by biological systems
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data from these studies are used in risk assessment, design and production of safer alternative chemicals, therapy for poisonings, treatment of disease; contributes to knowledge of basic physiology pharmacology, cell biology and biochem (basic science)
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29.
less than 24 hour exposure
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30.
when combined effect is equal to sum of the two compounds given alone

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