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Exam 3

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show toxicology  
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agent that can cause a deleterious response in a biological system   show
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show toxin  
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show toxicant  
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show xenobiotic  
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three approaches to toxicology (subject areas)   show
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show food, analytical/forensic, clinical, occupational, regulatory, environmental  
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show risk assessment and toxicogenomics  
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show Mechanistic  
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show Mechanistic  
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show descriptive toxicology  
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show Descriptive  
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science of determining if drugs and chemicals are safe for use... use information from descriptive and mechanistic toxicity data and epidemiology data (PAPER scientist)   show
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process to evaluate the potential for adverse health or environmental effects from exposure to naturally occuring or synthetic agents; includes estimate of probability of harm and description of assumptions and uncertainties that go into it   show
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show Risk Assessment  
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emerging sub-discipline of toxicology ; contibute to DNA; data from these techniques are descriptive but also provide info on mechanisms   show
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show forensics toxicology  
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show clinical toxicology  
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applies the principles and methodology of toxicology to chemical and biological hazards in the workplace   show
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they work to set levels for safe exposures to: environmental contaminants, food additives, medicinals   show
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show environmental technology  
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specialized areas of environmental toxicology; focuses on impacts of toxic substances on population dynamics in ecosystem   show
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three things importnant in environmental toxicology   show
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show 1958  
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exam for toxicology is administered by__________ and taken to become _________   show
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show need 2000 hrs of logged calls and 2000 hrs of other... take it every 7 years  
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no toxic effect unless poison:   show
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show chemical/physical properties, exposure, metabolized, concentration, susceptibility  
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show genetic predisposition, nonselective action, inappropriate use or admin  
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main reason drugs pulled from market   show
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show office in drug safety ; drug safety oversight board  
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show inhibits neuropathy target esterase so binds irreversible (delayed effect) --> 3-5 days later you get tingling and lose ability to move  
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when combined effect is equal to sum of the two compounds given alone   show
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when combined effect is much greater than the sum of the effects of each given alone   show
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when one subs. does not have a toxic effect but when added to another makes second compound more toxic than it would be alone   show
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when two compounds together interfere with each other's effect   show
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show tolerance  
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show dispositional tolerance  
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receptor expression repression   show
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principles of toxicology   show
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show subacute  
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show subchronic  
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exposure for more than 3 months   show
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less than 24 hour exposure   show
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Created by: aisdancer