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Hematology Tests 3-4 Test

Enter the letter for the matching Answer
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1.
What is a hemoglobinopathy?
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2.
What does Prussian blue stain?
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3.
Iron is bound to appoferritin or transferrin as . . .
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4.
What happens to the blood in chronic liver disease?
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5.
Free Erythrocyte Prophyrin
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6.
IDA serum Fe, TIBC, % saturation
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7.
Anemia of Chronic Disease differences from IDA
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8.
Patients with gastric resection can have IDA from . . .
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9.
What does the bone marrow of IDA look like?
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10.
What are some examples of intravascular hemolytic anemias?
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11.
ZPP
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12.
Hemochromatosis aka
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13.
What is a thalassemia?
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14.
Folic acid is absorbed in the . . .
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15.
Transferrin
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16.
Ferritin increased in . . .
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17.
What is the amino acid switch that causes sickle cell?
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18.
Common causes of Vit B12 Pernicious anemia
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19.
RDW range
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20.
What does the bone marrow in megaloblastic anemia look like?
A.
PNH; MAHA; DIC; Drug reaction in G6PD; transfusion reaction; Hereditary spherocytosis; H. eliptocytosis; H. pyropoikilocytosis; H. stomatocytosis
B.
impaired absorption
C.
Ferric (3+)
D.
iron transport protein; transfers in the 2+ state (ferrous)
E.
jejunum
F.
Beta chain, 6th position, Glu --> Val
G.
decreased; increased; decreased (less than 15%)
H.
A qualitative disorder in one of the chains of hemoglobin
I.
hypercellular with an increase in erythroid precursors and a decreased M:E ratio; cells show nuclear lagging (megaloblastic changes) "nuclear-cytoplasmic asyncrhony" - metamyelocytes and bands with loose chromatin; increased intercellular destruction
J.
typically causes macrocytic anemia; can cause codocytes and/or ecchinocytes
K.
any condition that leads to increased protein: hepatic necrosis; acute-phase reaction; sideroblastic anemia; hemochromatosis
L.
11.5-13.5% - greater than this indicates anisocytosis
M.
bronze diabetes
N.
can be normocytic/normochromic (or micro/hypo); normal to increased hemosiderin in bone marrow (it's there, just isn't released); normal to decreased TIBC; % saturation is >15% (this is key); normal to increased serum ferritin
O.
Iron deposits
P.
pretty much the same thing as ZPP, except instead of measuring porphyrin attached to zinc, you extract the free porphyrins from erythrocytes
Q.
A quanitative disorder of a hemoglobin chain (too much of one)
R.
zinc protoporphyrin; used as a screening test for lead poisoning; elevated in iron deficient conditions (most porphyrin chelates with zincion and makes ZPP)
S.
decreased M:E ratio, increased cellularity
T.
Dietary lack of B12 (not common in U.S.); antibodies against intrinsic factor
Type the Answer that corresponds to the displayed Question.
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21.
What is basophillic stippling composed of?
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22.
Serum Iron range
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23.
Congenital red cell aplasia is called . . .
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24.
What causes a vaso-oclusive crisis?
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25.
Ham's test aka . . .
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26.
Adult male IDA can result from . . .
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27.
Which age group is most affected by HUS?
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28.
glucose 6 phosphate dehydrogenase deficiencty; the most common erythorcyte enzyme disorder
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29.
Apoferritin (the protein) + iron
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30.
3+ state

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