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LU Lewis and Lecture notes

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Question
Answer
Epidermis   show
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dermis   show
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show fat, varies from person to person, regulates body temperature  
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show size, location, redness, edema, ecchymosis, drainage, approximation  
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show vasoconstriction (limit bleeding), followed by vasodilation (bring WBC to area, allows fluid to leak out of vascular) fibrin forms  
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cellular response   show
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show arrive first at injury (phagocytes). Eat, digest and produce waste products (pus), comes from the bone marrow  
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show infection in body so great depeletes mature WBC and the bone marrow sends out immature neutrophils (called bands) to help the fight. Check CBC for bands  
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monocytes   show
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show Complement system, 1-9 types. Complement deficiency means one is missing.  
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show chemical response, all irritate skin and cause pain and swelling, part of healing  
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show activate pathways that cause production of leukotrines (which cause anaphylactic reaction)  
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arterial problem   show
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venous problem   show
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show cidal, GI issues and rash, no toxicity, watch for anaphylaxisis, Gram +  
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show cidal, GI issues, no toxicity, cross reacts with PCN, Gram + and -. Most common antibiotics  
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Tetra (cycline)   show
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show static, GI and hepatic toxicity, OTO toxic and renal, take with water, no grapefruit juice, Gram +  
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show cidal, rash, GI, fatigue, irreversible Ototoxic, nephro toxic, Measure peaks and troughs, can affect coumadin. Gram - and some +  
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show static, GI, dysrhythmias, hepatotoxicity, tendon ruptures, anaphylactic, BS elevation, Gram + and pseudomonus  
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Sulfa (bactrim)   show
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Fever   show
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show antiprostaglandin meds. antipyretic, antiinflammatory, analgesic. mild to moderate GI effects  
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ASA   show
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show analagesic, high rate of death (in multiple meds patients OD without meaning to). liver toxic. Max dose 4000mg QD. Antidote is mucomist  
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show celebrex, block receptors. NOT antipyretic, no GI effects but possible cardiac effects  
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show hospital acquired  
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show smoking, immobility, nutrition, chronic diseases, meds, skin breakdown, environment  
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Phases of Wound Healing   show
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Inflammatory phase   show
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show 2 days to 3 weeks. Granulation (fibroblasts lay new collagen, fills defects and makes caps). Contraction (wound edges pull together). Epitheliazation (crosses moist surfaces 3 cm from good cell in all directions)  
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show 3 weeks to 2 years. New collagen forms (for strength) and scare tissue grows  
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show yeast, black tongue, caused by antibiotic use  
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antifungal meds   show
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show valtrex, treat virus. Liver toxic  
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tamiflu   show
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show Red (trauma or surgical wound: protect and clean) Yellow (prescence of slough and exudate: cleaning and removal of non viable tissue) Black (necrotic tissue: debridement)  
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show gauze, nonadherent dressings, transparent films, hydrocolloids, foams, absorptive dressings, hydrogel, alginates, antimicrobials  
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Reduce risk of pressure sore in Wheelchair   show
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show initial inflammatory response  
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show leukotrienes and prostoglandins  
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show decrease dosage  
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