LU Lewis and Lecture notes
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Epidermis | show 🗑
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dermis | show 🗑
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show | fat, varies from person to person, regulates body temperature
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show | size, location, redness, edema, ecchymosis, drainage, approximation
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show | vasoconstriction (limit bleeding), followed by vasodilation (bring WBC to area, allows fluid to leak out of vascular) fibrin forms
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cellular response | show 🗑
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show | arrive first at injury (phagocytes). Eat, digest and produce waste products (pus), comes from the bone marrow
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show | infection in body so great depeletes mature WBC and the bone marrow sends out immature neutrophils (called bands) to help the fight. Check CBC for bands
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monocytes | show 🗑
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show | Complement system, 1-9 types. Complement deficiency means one is missing.
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show | chemical response, all irritate skin and cause pain and swelling, part of healing
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show | activate pathways that cause production of leukotrines (which cause anaphylactic reaction)
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arterial problem | show 🗑
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venous problem | show 🗑
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show | cidal, GI issues and rash, no toxicity, watch for anaphylaxisis, Gram +
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show | cidal, GI issues, no toxicity, cross reacts with PCN, Gram + and -. Most common antibiotics
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Tetra (cycline) | show 🗑
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show | static, GI and hepatic toxicity, OTO toxic and renal, take with water, no grapefruit juice, Gram +
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show | cidal, rash, GI, fatigue, irreversible Ototoxic, nephro toxic, Measure peaks and troughs, can affect coumadin. Gram - and some +
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show | static, GI, dysrhythmias, hepatotoxicity, tendon ruptures, anaphylactic, BS elevation, Gram + and pseudomonus
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Sulfa (bactrim) | show 🗑
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Fever | show 🗑
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show | antiprostaglandin meds. antipyretic, antiinflammatory, analgesic. mild to moderate GI effects
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ASA | show 🗑
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show | analagesic, high rate of death (in multiple meds patients OD without meaning to). liver toxic. Max dose 4000mg QD. Antidote is mucomist
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show | celebrex, block receptors. NOT antipyretic, no GI effects but possible cardiac effects
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show | hospital acquired
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show | smoking, immobility, nutrition, chronic diseases, meds, skin breakdown, environment
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Phases of Wound Healing | show 🗑
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Inflammatory phase | show 🗑
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show | 2 days to 3 weeks. Granulation (fibroblasts lay new collagen, fills defects and makes caps). Contraction (wound edges pull together). Epitheliazation (crosses moist surfaces 3 cm from good cell in all directions)
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show | 3 weeks to 2 years. New collagen forms (for strength) and scare tissue grows
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show | yeast, black tongue, caused by antibiotic use
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antifungal meds | show 🗑
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show | valtrex, treat virus. Liver toxic
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tamiflu | show 🗑
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show | Red (trauma or surgical wound: protect and clean)
Yellow (prescence of slough and exudate: cleaning and removal of non viable tissue)
Black (necrotic tissue: debridement)
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show | gauze, nonadherent dressings, transparent films, hydrocolloids, foams, absorptive dressings, hydrogel, alginates, antimicrobials
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Reduce risk of pressure sore in Wheelchair | show 🗑
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show | initial inflammatory response
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show | leukotrienes and prostoglandins
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show | decrease dosage
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