Hematology Rodak chapters 13,14,16,17, 21, 38
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| How are plts released into peripheral circulate from the bone marrow? | show 🗑
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| show | Functional decline of several organ systems.
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| All of the following stimulate megakaryocyte and platelet production except: a. interlukins b. erythropoietin c. thrombopoietin d. CSF-Meg | show 🗑
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| what does the reticuloyte count assess? | show 🗑
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| From where are additional platelets first derived when the circulating count decreases? | show 🗑
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| show | adenosine diphosphate (ADP) release is inhibited.
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| show | produces energy for the cell
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| What are two key features with dimond blackfan anemia? | show 🗑
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| why are fat cells not seen in thin smear of bone marrow? | show 🗑
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| A bone marrow aspirate shows copious blue granulaes with the Prussian blue stain. | show 🗑
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| show | The formation and remodeling of bone
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| show | The re absorption of bone
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| Define ineffective erythropoesis. | show 🗑
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| show | Malignant cells
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| show | core biopsy
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| show | WBC begin to deteriorate 30 min after collection
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| What determines whether or not body fluids are diluted before counting? | show 🗑
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| The clinical consequences of panocytopenia? | show 🗑
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| show | The reduction in the number of erythrocytes, luekocytes, and thrombocytes
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| show | Add hyaluronidase to overcome the viscous nature of fluid
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| show | Marcrocytosis, thrombocytopenia, nutropenia
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| Bloody CSF in tube 1 and begins to clear as the tubes success indicate | show 🗑
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| show | Iron deficiency and anemia chronic c disease.
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| show | RDW
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| show | Pappenheimer body
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| DNA in a RBC | show 🗑
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| Precipitated RNA in a RBC | show 🗑
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| show | Heinz body
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| show | Anisocytosis is present
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| show | basophilic stippling
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| show | Should be drawn fasting in the morning
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| show | DNA
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| show | B12 and Folate
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| Which of the following is true regarding hypersegmented neutrophils? | show 🗑
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| show | Both the bone marrow and peripheral blood
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| What id the treatment of choice for long-term survival for patients under 40 yrs of age with aplastic anemia | show 🗑
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| show | Giant, multi nucleated red cells
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| show | Multi nucleated forms and intracellular bridges or nuclear strands between two erythroblasts
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| show | Giant erythroblasts with 12 nuclei are characteristic features.
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| Normal bone marrow cells being replaced with malignant cells is called? | show 🗑
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| show | Glycocalyx
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| show | endocytosis
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| show | MKI
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| Diploid and participates in normal mitosis | show 🗑
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| Transitional polyploidy is established | show 🗑
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| show | TPO or Erythropoietin
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| show | IL-3
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| Acts in the presence of TPO to enhance the later phenomena of endomitosis, Meg maturation and plt release | show 🗑
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| Synthesizes and stimulates plt production in chemo-induced thrombocytopenia | show 🗑
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| show | Dense Tubular system (DTS)
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| show | G-Protien
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| Twists spongelike and enables plts to store glycocalyx | show 🗑
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| what plt membrane receptor binds fibrinogen and supports plt aggregation? | show 🗑
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| show | GP Ib/ IX/ V
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| What plt membrane receptor binds directly to collagen of vascular matrix | show 🗑
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| show | Phosphatidylserine
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| What is the name of eicosanoid metabolite produced from endothelial cells that suppresses plt activation? | show 🗑
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| What binds membrane reseptors TP alpha or TP beta? | show 🗑
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| What allows Phospholipid #2 carbon to bind to unsaturated fatty acids | show 🗑
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| show | cycto oxygenase
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| show | Serotonin
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| show | VWF
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| show | P-selection
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| Reticulated plts can be enumerated in peripheral blood to detect...? | show 🗑
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| Plt adhesion refers to plts...what? | show 🗑
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| The prefered site for bone marrow biopsy in an adult is the? | show 🗑
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| The aspirate should be examined under low power to assess all of the following except: a. # of megakaryocytes b. cellularity c. Presence of tumor cells d. Morphology of abnormal cells | show 🗑
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| Normal M:E ratio | show 🗑
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| Most normoblasts in the normal marrow are? | show 🗑
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| show | Osteoblasts
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| The largest cell found in a normal bone marrow aspirate is the ? | show 🗑
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| show | Anemia w/ low serum iron and low ferritin
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| show | M:E ratio = 1.5:1
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| show | Osteoclats
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| What is the advantage of the core biopsy vs the aspirate? | show 🗑
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| Cells normally seen in CSF, serious and synovial fluids..? | show 🗑
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| "Fried egg" appearance | show 🗑
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| Idioplastic anemia is due to? | show 🗑
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| show | Destruction of stem cells by autoimmune t cells
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| show | Macrocytosis, thrombocytopenia, and neutropenia
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| show | Stem cell transplant from an HLA-identical sibling
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| Test most useful in differentiating FANCONI anemia from other causes of panocytopenia? | show 🗑
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| Mutation in genes that code for the telomerase complex may induce bone marrow failure | show 🗑
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| show | Only erythropoesis is affected
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| show | CDA
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| show | Inadequate production of erythropoietin
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| show | ?
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| show | ?
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| Morphology of lymphs of healthy children is? | show 🗑
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| show | ?
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| What are the most common anemias in elderly population | show 🗑
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| Iron deficiency is recognized in an elderly pt the cause is? | show 🗑
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| Which of the following conditions is least likely in an elderly pt | show 🗑
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