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pharm for Nat Board Review

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Question
Answer
The study of drugs and their effects on living organisms   Pharmocolgy  
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what the body does in response to the drugs (e.g., absorption, distribution, metabolism, excretion) is called?   Pharmacokinetics  
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amount of drug (e.g., in milligrams) needed to produce an effect; the more potent an agent is, the lower the dose needed to produce an effect   Potentcy  
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desired effect elicited by drug, independent of dose   Efficacy  
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Side effects fall under the category of adverse reactions, T or F   True  
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effect on an organ other than that intended to be altered (e.g., insomnia resulting from a bronchodilator); dose-related and often predictable   side effect  
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varies from mild rash to anaphylaxis; involves an antigen–antibody reaction (e.g., rash from penicillin); can include urticaria, soft-tissue swelling, and difficulty in breathing; not predictable and not dose-related   allergic reaction  
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Drug has an affinity for a receptor site and binds to it but produces no effect; competitively blocks the effect of the agonist   Antagonist  
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Drug has an affinity for a receptor site and binds to it producing an effect.   Agonist  
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The neurotransmitter for the Parasympathetic Nervous System (PANS) is ?   acetylcholine  
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The neurotransmitter for the Sympathetic Nervous System (SANS) is   adrenalin/epinephrine  
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Which part of the nervous system is active when the body is at ease?   parasympathetic  
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which part of the nervous system is active when the body is experiencing "fight or flight'?   sympathetic  
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drugs that imitate which neurotransmitter are known as parasympathomimetic or cholinergic drugs (P+)   acetylcholine  
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drugs that block or inhibit acetylcholine (P-) are known as what kind of drugs?   anticholinergic  
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The 2 types of receptors in the PANS are   muscarinic, nicotinic  
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drugs that imitate(SANS+) epinephrine are known as ?   sympathomimetic or adrenergic drugs  
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drugs that block or inhibit epinephrine (SANS-)are known as   sympatholytic or antiadrenergic drugs  
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what are the 2 types of receptors for the SANS   alpha and beta  
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Beta receptors of the SANS divide into 2 subclasses, what are they and what do they effect?   Beta 1 = heart, Beta 2= lungs and other tissues  
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Which receptor of the SANS is involved in the contraction of smooth muscle vasoconstriction?   Alpha  
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Which receptor of the SANS inhibits contraction, causing vasodialation?   Beta  
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In the blood vessels both alpha and beta receptors are present, however which receptors predominates?   Alpha  
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Which receptor of the SANS would you use to stimulate lower blood pressure   beta 1  
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which receptor of the SANS would you use to stimulate higher blood pressure?   beta 1, because a positive effect can increase the heart rate and a negative will decrease the heart rate.  
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Beta stimulation in the lungs results in?   Bronchodialation  
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Beta stimulation in the lungs results in?   Bronchodialation  
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A Cholinergic drug acts like acetlycholine (PANS)what are the general adverse effect of these drugs?   SLUD (salivation, lacrimation, urination, defacation)  
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A Cholinergic drug acts like acetlycholine (PANS)what are the general adverse effect of these drugs?   SLUD (salivation, lacrimation, urination, defacation)  
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If you needed to dry someone up name one drug you could give.   Atropine  
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If you needed to dry someone up name one drug you could give.   Atropine  
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For someone who had xerostomia or urinary retention what class of drug would you give?   Cholinergic - Xerostomia ie saligen  
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For someone who had xerostomia or urinary retention what class of drug would you give?   Cholinergic - Xerostomia ie saligen  
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A patient is going in for surgery and the surgeon wants to decrease salivary flow, urine flow etc...what class of drug does he/she give?   Anticholinergic such as Atropine  
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Scopolamine is a drug like atropine used to treat travel sickness (vomiting) what are the main side effect?   sedation, xerostomia and xeropathalmia (or dry eyes)  
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A patient is going in for surgery and the surgeon wants to decrease salivary flow, urine flow etc...what class of drug does he/she give?   Anticholinergic such as Atropine  
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Scopolamine is a drug like atropine used to treat travel sickness (vomiting) what are the main side effect?   sedation, xerostomia and xeropathalmia (or dry eyes)  
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