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Integumentary System

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Term
Definition
skin   organ covering the body; made up of layers  
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epidermis   outer layer of skin; protects the body from the external environment  
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keratin   scleroprotein component of the horny, or cornified, layer of the epidermis. Also, the primary component of the hair and nails  
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melanin   dark pigment produced by melanocytes; amount present determines skin color  
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hair   compressed, keratinized cells that arise from hair follicles, the sacs that enclose the hair fibers  
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nails   horny plates made from flattened epithelial cells; found on the dorsal surface of the ends of the fingers and toes  
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 sebaceous glands   secrete sebum (oil) into the hair follicles where the hair shafts pass through the dermis  
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 sudoriferous (sweat) glands   tiny, coiled, tubular structures that emerge through pores on the skin's surface and secrete sweat  
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dermis   inner layer of skin; responsible for its flexibility and mechanical strength  
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cutane/o, derm/o, dermat/o   skin  
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hidr/o   sweat  
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kerat/o   horny tissue (keratin), hard (Note: kerat/o is also used to refer to the cornea of the eye; see Chapter 12.)  
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onych/o, ungu/o   nail  
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seb/o   sebum (oil)  
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aut/o   self  
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bi/o   life  
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coni/o   dust  
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crypt/o   hidden  
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heter/o   other  
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myc/o   fungus  
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necr/o   death (cells, body)  
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pachy/o   thick  
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rhytid/o   wrinkles  
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staphyl/o   grapelike clusters  
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strept/o   twisted chains  
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xer/o   dry, dryness  
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epi-   on, upon, over  
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intra-   within  
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para-   beside, beyond, around, abnormal  
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per-   through  
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sub-   under, below  
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trans-   through, across, beyond  
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-a   noun suffix, no meaning  
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-coccus (pl. -cocci)   berry-shaped (form of bacterium)  
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-ectomy   excision or surgical removal  
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-ia   diseased or abnormal state, condition of  
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-itis   inflammation  
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-malacia   softening  
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-opsy   view of, viewing  
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-phagia   eating or swallowing  
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-plasty   surgical repair  
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-rrhea   flow, discharge  
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-tome   instrument used to cut  
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dermatitis   inflammation of the skin (Fig. 4.2)  
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dermatoconiosis   abnormal condition of the skin caused by dust  
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dermatofibroma   fibrous tumor of the skin  
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hidradenitis   inflammation of a sweat gland  
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keratosis   abnormal condition (growth) of horny tissue (keratin)  
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leiodermia   condition of smooth skin  
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onychocryptosis   abnormal condition of a hidden nail (also called ingrown nail)  
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onychomalacia   softening of the nails  
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onychomycosis   abnormal condition of a fungus in the nails (Exercise Figure B)  
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onychophagia   eating the nails (nail biting)  
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pachyderma   thickening of the skin  
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paronychia   diseased state around the nail (Exercise Figure B) (Note: the a from para- has been dropped. The final vowel in a prefix may be dropped when the word to which it is added begins with a vowel.)  
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seborrhea   discharge of sebum (excessive)  
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xanthoma   yellow tumor (benign, primarily in the skin)  
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xeroderma   dry skin (a mild form of a cutaneous disorder characterized by keratinization and noninflammatory scaling)  
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abrasion   scraping away of the skin by mechanical process or injury  
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abscess   localized collection of pus  
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acne   inflammatory disease of the skin involving the sebaceous glands and hair follicles  
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actinic keratosis   precancerous skin condition of horny tissue formation that results from excessive exposure to sunlight. It may evolve into a squamous cell carcinoma.  
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albinism   congenital hereditary condition characterized by partial or total lack of pigment (melanin) in the skin, hair, and eyes  
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basal cell carcinoma (BCC)   malignant epithelial tumor arising from the bottom layer of the epidermis called the basal layer; it seldom metastasizes, but invades local tissue and may recur in the same location. Common in individuals who have had excessive sun exposure. (Fig. 4.3)  
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candidiasis   infection of the skin, mouth (also called thrush), or vagina caused by the yeast-type fungus Candida albicans.  
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carbuncle   infection of skin and subcutaneous tissue composed of a cluster of boils (furuncles, see below) caused by staphylococcal bacteria  
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cellulitis   inflammation of the skin and subcutaneous tissue caused by infection; characterized by redness, pain, heat, and swelling  
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contusion   injury with no break in the skin, characterized by pain, swelling, and discoloration (also called a bruise)  
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eczema   noninfectious, inflammatory skin disease characterized by redness, blisters, scabs, and itching  
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fissure   slit or cracklike sore in the skin  
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furuncle   painful skin nodule caused by staphylococcal bacteria in a hair follicle (also called a boil) (Fig. 4.4)  
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gangrene   death of tissue caused by loss of blood supply followed by bacterial invasion (a form of necrosis)  
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herpes   inflammatory skin disease caused by herpes virus characterized by small blisters in clusters.  
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impetigo   superficial skin infection characterized by pustules and caused by either staphylococci or streptococci (see Table 4.1)  
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infection   invasion of pathogens in body tissue. An acute infection may remain localized if the body's defense mechanisms are effective or may persist to become subacute or chronic  
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Kaposi sarcoma   cancerous condition starting as purple or brown papules on the lower extremities that spreads through the skin to the lymph nodes and internal organs; frequently seen with AIDS  
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laceration   torn, ragged-edged wound  
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lesion   any visible change in tissue resulting from injury or disease. It is a broad term that includes sores, wounds, ulcers, and tumors.  
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MRSA infection   invasion of body tissue by methicillin-resistant Staphylococcus aureus, a strain of common bacteria that has developed resistance to methicillin and other antibiotics.  
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pediculosis   invasion into the skin and hair by lice  
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psoriasis   chronic skin condition producing red lesions covered with silvery scales  
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rosacea   chronic disorder of the skin that produces erythema, papules, pustules, and abnormal dilation of tiny blood vessels, usually occurring on the central area of the face in people older than 30 years (Fig. 4.5)  
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scabies   skin infection caused by the itch mite, characterized by papule eruptions that are caused by the female burrowing into the outer layer of the skin and laying eggs. This condition is accompanied by severe itching. (Table 4.1)  
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scleroderma   disease characterized by chronic hardening (induration) of the connective tissue of the skin and other body organs  
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squamous cell carcinoma (SCC)   malignant growth developing from scalelike epithelial tissue of the surface layer of the epidermis; it invades local tissue and may metastasize.  
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systemic lupus erythematosus (SLE)   chronic inflammatory disease involving the skin, joints, kidneys, and nervous system. This autoimmune disease is characterized by periods of remission and exacerbations. It also may affect other organs.  
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tinea   fungal infection of the skin. The fungi may infect keratin of the skin, hair, and nails. Infections are classified by body regions such as tinea capitis (scalp), tinea corporis (body), and tinea pedis (foot).  
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urticaria   itchy skin eruption composed of wheals of varying sizes and shapes. Urticaria is sometimes associated with infections and with allergic reactions to food, medicine, or other agents.  
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vitiligo   white patches on the skin caused by the destruction of melanocytes (Fig. 4.6)  
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Macule   flat, colored spot on the skin  
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Papule   small, solid skin elevation  
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Nodule   small, knotlike mass  
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Wheal   round, itchy elevation of the skin  
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Vesicle   small elevation of epidermis containing liquid  
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Pustule   elevation of the skin containing pus  
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Cyst   a closed sac containing fluid or semisolid material  
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cauterization   destruction of tissue with a hot or cold instrument, electric current, or caustic substance (also called cautery)  
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cryosurgery   destruction of tissue by using extreme cold, often by using liquid nitrogen (Fig. 4.8)  
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debridement   removal of contaminated or dead tissue and foreign matter from an open wound  
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dermabrasion   procedure to remove skin scars with abrasive material, such as sandpaper  
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excision   removal by cutting  
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incision   surgical cut or wound produced by a sharp instrument  
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incision and drainage (I&D)   surgical cut made to allow the free flow or withdrawal of fluids from a lesion, wound, or cavity  
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laser surgery   procedure using an instrument that emits a high-powered beam of light used to cut, burn, vaporize, or destroy tissue  
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Mohs surgery   technique of microscopically controlled serial excisions of a skin cancer  
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suturing   to stitch edges of a wound surgically (Fig. 4.9)  
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dermatologist   physician who studies and treats skin (diseases)  
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dermatology   study of the skin (branch of medicine that deals with the diagnosis and treatment of skin diseases)  
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epidermal   pertaining to upon the skin  
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erythroderma   red skin (abnormal redness of the skin) (Exercise Figure C)  
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hypodermic   pertaining to under the skin (Exercise Figure D)  
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intradermal (ID)   pertaining to within the skin (Exercise Figure D)  
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keratogenic   producing horny tissue  
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leukoderma   white skin (white patches caused by depigmentation) (Exercise Figure C)  
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necrosis   abnormal condition of death (cells and tissue die because of disease)  
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percutaneous   pertaining to through the skin  
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staphylococcus (pl. staphylococci) (staph)   berry-shaped (bacterium) in grapelike clusters (these bacteria cause many skin diseases) (Exercise Figure E)  
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streptococcus (pl. streptococci) (strep)   berry-shaped (bacterium) in twisted chains (Exercise Figure F)  
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subcutaneous (subcut)   pertaining to under the skin (Exercise Figure D)  
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subungual   pertaining to under the nail  
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transdermal (TD)   pertaining to through the skin (Exercise Figure D)  
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ungual   pertaining to the nail  
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xanthoderma   yellow skin (Exercise Figure C)  
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xerosis   abnormal condition of dryness (of skin, eye, or mouth)  
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alopecia   loss of hair (Fig. 4.10)  
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bacteria (s. bacterium)   single-celled microorganisms that reproduce by cell division and may cause infection by invading body tissue  
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cicatrix   scar  
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cyst   closed sac containing fluid or semisolid material (Table 4.2)  
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cytomegalovirus   herpes-type virus that usually causes disease when the immune system is compromised  
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diaphoresis   sweating  
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ecchymosis (pl. ecchymoses)   escape of blood into the skin (or mucous membrane), causing a small, flat, purple, or blue discoloration, as may occur when blood is withdrawn by a needle and syringe from an arm vein  
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edema   puffy swelling of tissue from the accumulation of fluid  
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erythema   redness  
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fungus (pl. fungi)   organism that feeds by absorbing organic molecules from its surroundings and may cause infection by invading body tissue; single-celled fungi (yeast) reproduce by budding; multicelled fungi (mold) reproduce by spore formation  
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induration   abnormal hard spot(s) or area of skin; may include underlying tissue  
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jaundice   condition characterized by a yellow coloring of the skin, mucous membranes, and sclera (whites of the eyes) caused by the presence of bile (also called icterus)  
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keloid   overgrowth of scar tissue (Fig. 4.11)  
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leukoplakia   condition characterized by white spots or patches on mucous membrane, which may be precancerous  
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macule   flat, colored spot on the skin (Table 4.2)  
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nevus (pl. nevi)   circumscribed malformation of the skin, usually brown, black, or flesh colored. A congenital nevus is present at birth and is referred to as a birthmark. (also called a mole) (Fig. 4.12)  
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nodule   small, knotlike mass that can be felt by touch (Table 4.2)  
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pallor   paleness  
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papule   small, solid skin elevation (Table 4.2)  
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petechia (pl. petechiae)   pinpoint skin hemorrhage  
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pressure injury   damage of the skin and the subcutaneous tissue caused by prolonged pressure, often occurring in bedridden patients; the injury, which may be painful, can present as intact skin or an open ulcer.  
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pruritus   itching  
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purpura   small hemorrhages in the skin (or mucous membrane), giving a purple-red discoloration; associated with blood disorders or vascular abnormalities  
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pustule   elevation of skin containing pus (Table 4.2)  
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ulcer   erosion of the skin or mucous membrane  
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verruca   circumscribed cutaneous elevation caused by a virus (also called wart) (Fig. 4.13)  
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vesicle   small elevation of the epidermis containing liquid (also called blister) (Table 4.2)  
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virus   minute microorganism, much smaller than a bacterium, characterized by a lack of independent metabolism and the ability to replicate only within living host cells; may cause infection by invading body tissue  
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wheal   transitory, itchy elevation of the skin with a white center and a red surrounding area; a wheal is an individual urticaria (hive) lesion  
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BCC   basal cell carcinoma  
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bx   biopsy  
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CMV   cytomegalovirus  
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CA-MRSA   community-associated MRSA infection  
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derm   dermatology  
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HA-MRSA   healthcare-associated MRSA infection  
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I&D   incision and drainage  
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ID   intradermal  
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MRSA   methicillin-resistant Staphylococcus aureus  
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SCC   squamous cell carcinoma  
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SLE   systemic lupus erythematosus  
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staph   staphylococcus  
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strep   streptococcus  
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subcut   subcutaneous  
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TD   transdermal  
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