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chapter 4

Integumentary System

TermDefinition
skin organ covering the body; made up of layers
epidermis outer layer of skin; protects the body from the external environment
keratin scleroprotein component of the horny, or cornified, layer of the epidermis. Also, the primary component of the hair and nails
melanin dark pigment produced by melanocytes; amount present determines skin color
hair compressed, keratinized cells that arise from hair follicles, the sacs that enclose the hair fibers
nails horny plates made from flattened epithelial cells; found on the dorsal surface of the ends of the fingers and toes
 sebaceous glands secrete sebum (oil) into the hair follicles where the hair shafts pass through the dermis
 sudoriferous (sweat) glands tiny, coiled, tubular structures that emerge through pores on the skin's surface and secrete sweat
dermis inner layer of skin; responsible for its flexibility and mechanical strength
cutane/o, derm/o, dermat/o skin
hidr/o sweat
kerat/o horny tissue (keratin), hard (Note: kerat/o is also used to refer to the cornea of the eye; see Chapter 12.)
onych/o, ungu/o nail
seb/o sebum (oil)
aut/o self
bi/o life
coni/o dust
crypt/o hidden
heter/o other
myc/o fungus
necr/o death (cells, body)
pachy/o thick
rhytid/o wrinkles
staphyl/o grapelike clusters
strept/o twisted chains
xer/o dry, dryness
epi- on, upon, over
intra- within
para- beside, beyond, around, abnormal
per- through
sub- under, below
trans- through, across, beyond
-a noun suffix, no meaning
-coccus (pl. -cocci) berry-shaped (form of bacterium)
-ectomy excision or surgical removal
-ia diseased or abnormal state, condition of
-itis inflammation
-malacia softening
-opsy view of, viewing
-phagia eating or swallowing
-plasty surgical repair
-rrhea flow, discharge
-tome instrument used to cut
dermatitis inflammation of the skin (Fig. 4.2)
dermatoconiosis abnormal condition of the skin caused by dust
dermatofibroma fibrous tumor of the skin
hidradenitis inflammation of a sweat gland
keratosis abnormal condition (growth) of horny tissue (keratin)
leiodermia condition of smooth skin
onychocryptosis abnormal condition of a hidden nail (also called ingrown nail)
onychomalacia softening of the nails
onychomycosis abnormal condition of a fungus in the nails (Exercise Figure B)
onychophagia eating the nails (nail biting)
pachyderma thickening of the skin
paronychia diseased state around the nail (Exercise Figure B) (Note: the a from para- has been dropped. The final vowel in a prefix may be dropped when the word to which it is added begins with a vowel.)
seborrhea discharge of sebum (excessive)
xanthoma yellow tumor (benign, primarily in the skin)
xeroderma dry skin (a mild form of a cutaneous disorder characterized by keratinization and noninflammatory scaling)
abrasion scraping away of the skin by mechanical process or injury
abscess localized collection of pus
acne inflammatory disease of the skin involving the sebaceous glands and hair follicles
actinic keratosis precancerous skin condition of horny tissue formation that results from excessive exposure to sunlight. It may evolve into a squamous cell carcinoma.
albinism congenital hereditary condition characterized by partial or total lack of pigment (melanin) in the skin, hair, and eyes
basal cell carcinoma (BCC) malignant epithelial tumor arising from the bottom layer of the epidermis called the basal layer; it seldom metastasizes, but invades local tissue and may recur in the same location. Common in individuals who have had excessive sun exposure. (Fig. 4.3)
candidiasis infection of the skin, mouth (also called thrush), or vagina caused by the yeast-type fungus Candida albicans.
carbuncle infection of skin and subcutaneous tissue composed of a cluster of boils (furuncles, see below) caused by staphylococcal bacteria
cellulitis inflammation of the skin and subcutaneous tissue caused by infection; characterized by redness, pain, heat, and swelling
contusion injury with no break in the skin, characterized by pain, swelling, and discoloration (also called a bruise)
eczema noninfectious, inflammatory skin disease characterized by redness, blisters, scabs, and itching
fissure slit or cracklike sore in the skin
furuncle painful skin nodule caused by staphylococcal bacteria in a hair follicle (also called a boil) (Fig. 4.4)
gangrene death of tissue caused by loss of blood supply followed by bacterial invasion (a form of necrosis)
herpes inflammatory skin disease caused by herpes virus characterized by small blisters in clusters.
impetigo superficial skin infection characterized by pustules and caused by either staphylococci or streptococci (see Table 4.1)
infection invasion of pathogens in body tissue. An acute infection may remain localized if the body's defense mechanisms are effective or may persist to become subacute or chronic
Kaposi sarcoma cancerous condition starting as purple or brown papules on the lower extremities that spreads through the skin to the lymph nodes and internal organs; frequently seen with AIDS
laceration torn, ragged-edged wound
lesion any visible change in tissue resulting from injury or disease. It is a broad term that includes sores, wounds, ulcers, and tumors.
MRSA infection invasion of body tissue by methicillin-resistant Staphylococcus aureus, a strain of common bacteria that has developed resistance to methicillin and other antibiotics.
pediculosis invasion into the skin and hair by lice
psoriasis chronic skin condition producing red lesions covered with silvery scales
rosacea chronic disorder of the skin that produces erythema, papules, pustules, and abnormal dilation of tiny blood vessels, usually occurring on the central area of the face in people older than 30 years (Fig. 4.5)
scabies skin infection caused by the itch mite, characterized by papule eruptions that are caused by the female burrowing into the outer layer of the skin and laying eggs. This condition is accompanied by severe itching. (Table 4.1)
scleroderma disease characterized by chronic hardening (induration) of the connective tissue of the skin and other body organs
squamous cell carcinoma (SCC) malignant growth developing from scalelike epithelial tissue of the surface layer of the epidermis; it invades local tissue and may metastasize.
systemic lupus erythematosus (SLE) chronic inflammatory disease involving the skin, joints, kidneys, and nervous system. This autoimmune disease is characterized by periods of remission and exacerbations. It also may affect other organs.
tinea fungal infection of the skin. The fungi may infect keratin of the skin, hair, and nails. Infections are classified by body regions such as tinea capitis (scalp), tinea corporis (body), and tinea pedis (foot).
urticaria itchy skin eruption composed of wheals of varying sizes and shapes. Urticaria is sometimes associated with infections and with allergic reactions to food, medicine, or other agents.
vitiligo white patches on the skin caused by the destruction of melanocytes (Fig. 4.6)
Macule flat, colored spot on the skin
Papule small, solid skin elevation
Nodule small, knotlike mass
Wheal round, itchy elevation of the skin
Vesicle small elevation of epidermis containing liquid
Pustule elevation of the skin containing pus
Cyst a closed sac containing fluid or semisolid material
cauterization destruction of tissue with a hot or cold instrument, electric current, or caustic substance (also called cautery)
cryosurgery destruction of tissue by using extreme cold, often by using liquid nitrogen (Fig. 4.8)
debridement removal of contaminated or dead tissue and foreign matter from an open wound
dermabrasion procedure to remove skin scars with abrasive material, such as sandpaper
excision removal by cutting
incision surgical cut or wound produced by a sharp instrument
incision and drainage (I&D) surgical cut made to allow the free flow or withdrawal of fluids from a lesion, wound, or cavity
laser surgery procedure using an instrument that emits a high-powered beam of light used to cut, burn, vaporize, or destroy tissue
Mohs surgery technique of microscopically controlled serial excisions of a skin cancer
suturing to stitch edges of a wound surgically (Fig. 4.9)
dermatologist physician who studies and treats skin (diseases)
dermatology study of the skin (branch of medicine that deals with the diagnosis and treatment of skin diseases)
epidermal pertaining to upon the skin
erythroderma red skin (abnormal redness of the skin) (Exercise Figure C)
hypodermic pertaining to under the skin (Exercise Figure D)
intradermal (ID) pertaining to within the skin (Exercise Figure D)
keratogenic producing horny tissue
leukoderma white skin (white patches caused by depigmentation) (Exercise Figure C)
necrosis abnormal condition of death (cells and tissue die because of disease)
percutaneous pertaining to through the skin
staphylococcus (pl. staphylococci) (staph) berry-shaped (bacterium) in grapelike clusters (these bacteria cause many skin diseases) (Exercise Figure E)
streptococcus (pl. streptococci) (strep) berry-shaped (bacterium) in twisted chains (Exercise Figure F)
subcutaneous (subcut) pertaining to under the skin (Exercise Figure D)
subungual pertaining to under the nail
transdermal (TD) pertaining to through the skin (Exercise Figure D)
ungual pertaining to the nail
xanthoderma yellow skin (Exercise Figure C)
xerosis abnormal condition of dryness (of skin, eye, or mouth)
alopecia loss of hair (Fig. 4.10)
bacteria (s. bacterium) single-celled microorganisms that reproduce by cell division and may cause infection by invading body tissue
cicatrix scar
cyst closed sac containing fluid or semisolid material (Table 4.2)
cytomegalovirus herpes-type virus that usually causes disease when the immune system is compromised
diaphoresis sweating
ecchymosis (pl. ecchymoses) escape of blood into the skin (or mucous membrane), causing a small, flat, purple, or blue discoloration, as may occur when blood is withdrawn by a needle and syringe from an arm vein
edema puffy swelling of tissue from the accumulation of fluid
erythema redness
fungus (pl. fungi) organism that feeds by absorbing organic molecules from its surroundings and may cause infection by invading body tissue; single-celled fungi (yeast) reproduce by budding; multicelled fungi (mold) reproduce by spore formation
induration abnormal hard spot(s) or area of skin; may include underlying tissue
jaundice condition characterized by a yellow coloring of the skin, mucous membranes, and sclera (whites of the eyes) caused by the presence of bile (also called icterus)
keloid overgrowth of scar tissue (Fig. 4.11)
leukoplakia condition characterized by white spots or patches on mucous membrane, which may be precancerous
macule flat, colored spot on the skin (Table 4.2)
nevus (pl. nevi) circumscribed malformation of the skin, usually brown, black, or flesh colored. A congenital nevus is present at birth and is referred to as a birthmark. (also called a mole) (Fig. 4.12)
nodule small, knotlike mass that can be felt by touch (Table 4.2)
pallor paleness
papule small, solid skin elevation (Table 4.2)
petechia (pl. petechiae) pinpoint skin hemorrhage
pressure injury damage of the skin and the subcutaneous tissue caused by prolonged pressure, often occurring in bedridden patients; the injury, which may be painful, can present as intact skin or an open ulcer.
pruritus itching
purpura small hemorrhages in the skin (or mucous membrane), giving a purple-red discoloration; associated with blood disorders or vascular abnormalities
pustule elevation of skin containing pus (Table 4.2)
ulcer erosion of the skin or mucous membrane
verruca circumscribed cutaneous elevation caused by a virus (also called wart) (Fig. 4.13)
vesicle small elevation of the epidermis containing liquid (also called blister) (Table 4.2)
virus minute microorganism, much smaller than a bacterium, characterized by a lack of independent metabolism and the ability to replicate only within living host cells; may cause infection by invading body tissue
wheal transitory, itchy elevation of the skin with a white center and a red surrounding area; a wheal is an individual urticaria (hive) lesion
BCC basal cell carcinoma
bx biopsy
CMV cytomegalovirus
CA-MRSA community-associated MRSA infection
derm dermatology
HA-MRSA healthcare-associated MRSA infection
I&D incision and drainage
ID intradermal
MRSA methicillin-resistant Staphylococcus aureus
SCC squamous cell carcinoma
SLE systemic lupus erythematosus
staph staphylococcus
strep streptococcus
subcut subcutaneous
TD transdermal
Created by: noellecorrinne
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