General Surgery
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Which types of medications should be stopped preoperatively? | 1) Anticoagulants
2) Antiplatelets
3) Diabetic medications
4) ACEIs and statins
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When do we perform CBCs preoperatively? | As baseline
If the estimated blood loss is >500mL
In patients with chronic illness or anemia
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When do we perform urine analysis preoperatively? | Urological symptoms present
Instruments in UT
Possible surgical placement of prosthesis
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When do we check serum electrolytes preoperatively? | If the patient is >50
Chronic diarrhea
Major procedures
Renal, liver, cardiac disease
HTN, DM
Diuretic use, digoxin use, ACEI use
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When do we perform coagulation studies preoperatively? | Anticoagulant use
Family history of bleeding disorders
History of abnormal bleeding
Liver disease, malnutrition, and alcohol use
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When do we test Beta-hCG preoperatively? | In any patient within the childbearing age
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When do we test LFTs preoperatively? | Major procedure
History of liver or biliary disease
Albumin is a strong predictor for preoperative morbidity
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When do cross-match blood preoperatively? | If estimated blood loss is >500 mL
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When do we perform a chest x-ray preoperatively? | Acute cardiac or pulmonary symptoms
Smokers
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When do you perform ECGs preoperatively? | All patients >50
Patients with known heart disease
Diabetic patients
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What are the cardiovascular risks which increase morbidity in surgery? | Age >70
DM
Unstable angina
Recent MI (within 6 months)
CHF
Valvular heart disease
Arrhythmias
Peripheral vascular disease
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Which drugs reduce peri-operative risk of cardiac events and MI? | Beta blockers
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What are the pulmonary risks which increase morbidity in surgery? | COPD
Smoking
Advanced age
Obesity
Acute RTI
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Which tests should be performed preoperatively in patients with a history of lung disease or smoking? | ABGs
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What test should be done in a patient >30 years of age with breathlessness? | ECG
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What are the renal risks which increase morbidity in surgery? | DM
HTN
CAD
Hyperkalemia
IV volume overload
Infectious complications
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What questions do you want to ask in the history of a patient with CKD? | Is it due to HT or DM?
When was your first dialysis?
How much fluid was removed?
What is your preoperative weight?
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How do you assess volume status in physical examination? | JVP and lung crackles
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What investigations do we perform in patients with renal risk? | CBC, electrolytes, creatinine, BUN
Urine analysis and culture
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How do you manage patients with CKD? | Dialysis within 24 hours of surgery
Intravascular volume status monitoring
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What is the risk of AKI in patients without preexisting CKD for cardiac surgery and patients undergoing AAA repair? | 1.5-2.5%
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What are the indications for dialysis? | Intavascular volume overload
Hyperkalemia
Severe metabolic acidosis
Complications of uremia (encephalopathy,
pericarditis)
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What are the risk factors for AKI? | Increased BUN/ increased Creatinine
CHD/introperative hypotension
Advanced age
Sepsis
Administration of nephrotoxic substances
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What post-operative events increase the chance of CVA? | A-fib
Hypotensions
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What are the types of wounds, according to the surgical procedure? | Clean
Clean, contaminated
Contaminated
Dirty
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What is the definition of a clean wound? | Non-traumatic
No entry of GI, biliary, tracheobronchial, respiratory, or gut
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What are some examples of clean wounds? | Wide, local excision of mass
Hernia repair
Thyroid surgeries
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What is the definition of clean-contaminated wounds? | Respiratory, GU, GI entry with minimal contamination
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What are some examples of clean-contaminated wounds? | Gastrectomy
Hysterectomy
Cholecystectomy
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What is the definition of contaminated wounds? | Open, fresh traumatic wounds
Uncontrolled spillage from poorly prepared hollow viscus
Minor breaks in sterile techniques
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What are some examples of contaminated wounds? | Ruptured Appendix
Resection of unprepared bowel
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What is the definition of dirty wounds? | Open, traumatic, dirty wounds
Traumatic perforated viscus
Pus in the operative field
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What are some examples of dirty wounds? | Intestinal fistula resection
Hartman’s for diverticular perforation
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What are the risks of contamination in the different types of wounds? | Clean --> 2%
Clean-contaminated --> <10 %
Contaminated --> 20%
Dirty --> 30-70%
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What are the methods of prophylaxis of of preventing infections? | Strict sterile techniques
Maintaining normal body temperature, blood glucose levels, and
hyperoxygenation
Pre-operative skin antisepsis by chlorhexidine-alcohol (better) or using Povidone-iodine scrub
Antibiotic prophylaxis
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What are the likely pathogens in cardiac operations? | Staphylococci
Corynebacteria
Enteric gram negative bacilli
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What are the recommended antibiotics in cardiac surgery? | Vancomycin, cefazolin, and aztreonam
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What are the likely pathogens in thoracic surgery? | Staphylococci
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What are the recommended antibiotics in thoracic surgery? | Cefazolin
Vancomycin
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What are the likely pathogens in vascular surgery? | Staphylococci
Streptococci
Enteric grame negative bacilli
Clostridia
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What are the recommended antibiotics in vascular surgery? | Cefazolin
Vancomycin and Aztreonam
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What are the likely pathogens in orthopedics surgery? | Staphylococci
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What are the recommended antibiotics in orthopedics surgery? | Cefazolin
Vancomycin
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What are the likely pathogens in Upper GI and hepato-biliary surgery? | Enteric gram negative bacilli
Enterococci
Clostridia
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What are the recommended antibiotics in upper GI and hepatobiliary surgery? | Cefazolin
Cefatetran
Cefoxitin
Clindamycin + Gentamycin (if allergic)
Ciprofloxacin + metronidazole
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What are the likely pathogens in appendectomy and colorectal surgery? | Gram-negative bacilli
Enterococci
Anaerobes
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What are the recommended antibiotics in appendectomy and colorectal surgery? | Cefoxiting
Cefotetan
Ciprofloxacin and Metronidazole
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What are the likely pathogens in OBGYN surgery? | Gram negative bacilli
Anaerobes
Group B steptococci
Enterococci
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What are the recommend antibiotics in OBGYN surgery? | Cefatetan
Cefoxitin
Cefazolin
Clindamycin + Gentamycin
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When undergoing and elective surgery, blood glucose levels should be controlled between | 100-250
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Patients on oral hypoglycemic agents should discontinue their medications | The night before the surgery
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Patients on insulin undergoing major surgeries should receive: | ½ their insulin dose and 5% dextrose IV at 100-125 mL/hour
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It is considered safe to perform surgery when INR is | <1.5
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If the INR is high before an emergency procedure, you should give: | you can either give factor VIII (immediately effective) or vitamin K (effective within 8 hours)
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Most common indications for warfarin treatment: | Atrial fibrillation
Venous thromboembolism
Mechanical heart valve
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How do you activate the pulmonary toiler postoperatively? | Early mobilization
Incentive spirometry
Cough
Deep breathing exercises
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What are the consequences of inadequate pulmonary toilet? | Fever, hypoxemia, pneumonia, and atelactasis
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What medications are generally given to a patient post-op? | Antiemetics
Ulcer prophylaxis (sucralfate)
Morphine
Antibiotics
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What lab investigations are performed in a post operative patient? | CBC and coagulation (in significant blood loss)
KFT (in insufficiency, large IV fluid volumes, TPN, tranfusion, NPO)
Daily EGH and 3 troponin 3 levels (in cardiac risk factor patients)
Chest X-ray (if thoracic cavity involved/cardiopulmonary risk)
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What are the intraoperative causes of fever? | Malignant hyperthermia
Transfusion reaction
Pre-existing infection
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What are the postoperative causes of fever? | Wind/Atelactasis (first 2 days)
Water/UTI (3rd day)
Wound (5th day)
Walking/DVT (7-10 days)
Wonder drug
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Which bacteria can cause fever in the first 2 days after an operation? | Beta hemolytic strep or clostridium
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Clostridium infections appear as | Painful bronze/brown weeping wounds
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What is the treatment of malignant hyperthermia? | Dantrolene (antidote)
100% oxygen
Correct acidosis and cooling blankets
Water for developing myoglobinurea
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What is the clinical presentation of post-op MI? | Often without chest pain
New onset congestive heart failure
New onset cardiac arrhythmias
Abnormal vital signs: hypotension, tachypnea, tachycardia, or
bradycardia
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Treatment of post-op MI: | MONAH-B
Morphine
Oxygen
Nitrates
Aspirin
Heparin
Beta blockers
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What are the risk factors for atelactasis post-op? | COPD/smoking
Abdominal/thoracic surgery
Poor pain control: patient cannot breathe in deeply secondary to pain on inspiration
Oversedation
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What are the signs of atelactasis? | Fever, tachypnea, and tachycardia
Decreased breath sounds with crackles
Increased density on chest X-ray
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What is the treatment for post-op atelactasis? | Postoperative incentive spirometry
Deep breathing exercises
Coughing
Early ambulation
Chest and physiotherapy along with NT suction
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What are the risk factors for aspiration pneumonia? | Intubation/extubation
Chest pain
Increased Impaired level of consciousness (drugs/ethanol
overdose)
NG tube
Tendelburg position
Emergent intubation on full stomach
Gastric dilation
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What are the common sites of aspiration pneumonia? | Supine: right upper lobe
Sitting/semi-recumbent: right lower lobe
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What are the common causes of urine retention post-op? | Enlarged urinary bladder resulting from medications or spinal anesthesia
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What is the treatment of post-op urine retention? | Urinary catheter (Foleys)
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How do you drain a massive urinary bladder? | Don’t drain all urine immediately to avoid a vasovagal reaction. Clamp after draining 1 liter of urine, then drain the rest slowly
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The classic symptom of urinary retention in elderly is | Confusion
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What are the differential diagnoses in postoperative renal failure? | Prerenal: inadequate perfusion
Renal: kidney parynchemal dysfunction
Postrenal: obstruction to outflow of urine
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How do you interpret the work up to differentiate between Pre-renal and renal failure? | BUN: Cr
>20:1 pre-renal
<20:1 renal
Specific gravity:
>1.02 Pre-renal
<1.02 renal
Urine Na:
<20 pre renal
>40 renal
Urine osmolality
>500 pre renal
<350 renal
FENa
<1% pre-renal
>1% renal
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What are the indications for dialysis? | Fluid overload
Refractory hypotension
Severe metabolic acidosis
BUN >130
Uremic complications
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What are the post-op neurological complications? | Delirium tremans
Postop CVA
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How do you treat delirium tremans? | IV benzodiazepenes
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How do you treat post-op CVA? | Aspirin and Heparin
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What are the possible complications of NG tube insertion? | Aspiration pneumonia
Atelactasis if the tube is clogged
Sinusitis
Minor upper GI bleeding
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What are the postop causes of paralytic ileus? | Lapotomy
Hypokalemia
Narcotics
Intraperitoneal infection
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What is short bowel syndrome? | malabsorption and diarrhea resulting from extensive
bowel resection (<120 cm of small intestines remaining)
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How is short bowel syndrome treated? | With TPN followed by many small meals chronically
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What is Blind loop syndrome? | Bacterial overgrowth in the small intestines
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What are the causes of post-op B12 deficiency? | Gastrectomy (decreased secretion of intrinsic factor)
Excision of terminal ileum (site of B12 absorption)
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What is Dumping syndrome? | Delivery of hyperosmotic chyme to the small intestine causing massive fluid shifts into the bowel
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What are the signs and symptoms of Dumping syndrome? | Post prandial diaphoresis
Tachycardia
Emesis
Dizziness, weakness
Increased flatus
Abdominal pain and distention
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What are the causes of prehepatic jaundice? | Hemolysis
Resolving hematoma
Transfusion reaction
Post-cardiopulmonary bypass
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What are the causes of hepatic jaundice? | Drugs
Hypotension/hypoxia
Sepsis
Pre-existing cirrhosis
Right sided heart failure
Gilbert/ Criglar-Najjar syndrome
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What are the causes of posthepatic jaundice? | Choledocholithiasis
Stricture
Cholangitis
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What are the post-op infectious complications? | Catheter related infection
Prosthetic device related
Facial muscle infection
Intra-abdominal abscess/peritonitis
Respiratory/GI/GU infection
Wound infection
Patients requiring mechanical ventilation for longer than 48 hours
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When are potassium supplements contraindicated? | ECG changes or when potassium >6
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What are the potassium supplement doses recommended at different potassium levels? | <3: 30-40 mg/hour
3-4: 20-30 mg/hour
>4 10-20 mg/hour
5
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When do you give bicarbonate to a DKA patient? | If the pH is <7.1
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