Thyroid
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| iodine deficiency leads to lack of thyroid hormone production (Hypothyroidism). | Leads to mental retardation, cretinism in fetus
🗑
|
||||
| T3 is 4-8x more active metabolically than T4. T3 is ‘active’ form of thyroid hormone; T4 ‘pre-’ hormone; thyroglobulin ‘pro’ hormone | Released T4 converted to T3 by liver and kidney
🗑
|
||||
| Three major thyroid hormone binding proteins: 1. Thyroxine-binding globulin (TBG) 2. Thyroxine-binding prealbumin (TBPA; transthyretin) 3. Albumin T4 and T3 levels affected by levels of available binding proteins. |
🗑
|
||||
| Graves’ disease: most common cause of hyperthyroidism; antibody to TSH receptor protein; receptor stimulation leads to thyroid growth; excessive levels of thyroid hormone produced; diagnosed with tests to measure antibodies to TSH receptor. | Lab testing: high free T4 and/or T3 level with undetectable TSH; thyroid stimulating antibodies (TSIs) and TSH receptor antibodies usually positive.
🗑
|
||||
| Chronic lymphocytic thyroiditis (Hashimoto’s thyroiditis): hypothyroidism; antibodies result in decreased thyroid hormone production | Low free T4 level with a normal or high TSH
🗑
|
||||
| TSH Specimen collection and storage: serum or plasma with EDTA or heparin. Specimens stable at 4oC for 24h or -20oC for 1 month. | Reference Intervals (Total T4; nmol/L): Adults: Males and females 59-135nmol/L.
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
mastergogo
Popular Laboratory Science sets