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Keywords for Evidence Based Practices for Healthcare Chapter 1

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Term
Definition
Thalidomide   a sedative hypnotic drug that was originally used to treat morning sickness & help pregnant women sleep; causes phocomelia in infants (seal-limb).  
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Phocomelia   a birth defect in which the long bones of the arms and legs don't form properly such that the hand or foot attaches to the body by a short stump resembling a flipper.  
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Evidence-based practice (EBP)   process of combining best available research evidence with your knowledge and skill to make collaborative, patient or population-centered decisions w/in context of a given healthcare situation.  
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Translational critical thinking   Application of critical thinking where theoretical skills & concepts of critical thinking are enacted to solve real-world, ill-structured problems; Requires self-awareness, intellectual humility, self-direction & active learning.  
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USPSTF (U.S. Preventive Services Task Force)   agency w/in AHRQ; independent group of national experts in prevention & evidence-based medicine that work improve health of all Americans by making evidence-based recommendations about clinical preventive services (screenings, counseling, preventive).  
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Mortality   death, or rate death associated with a given health problem or intervention  
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Morbidity   diseased state/illness  
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Surrogate Outcome   process of using one outcome to reflect another  
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Outcomes that matter   clinically relevant outcomes provide direct measures of functioning or disease; includes other outcomes that patients & providers care about; (mortality, quality of life, cost, patient function).  
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Focused clinical questions   questions formulated around a clinical information need; 3 elements: (1) specific conditioner outcome; (2) patient demographics; (3) patient risk factors  
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Prospective EBP   Seeking information in advance, rather than only in response to patient encounters. Developing your knowledge & drawing on it in clinical situations. Making habit of searching for latest developments in your areas of interest and practice (AKA "scanning")  
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Concurrent EBP   Looking up information in response to clinical questions & using that information to make decisions regarding an individual patient. (may occur while pt is in in clinic).  
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Retrospective EBP   looking up information subsequent to a clinical encounter  
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Critical appraisal   Process of evaluating trustworthiness & relevance of a resource w/in context of a given clinical situation. (Potential sources of bias, sample representation, method consistency in regards to question explored, common sense of a study.)  
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Secondary literature   summary, interpretation, evaluation of primary literature, such as traditional literature review. Practice guidelines & position papers may also fall int his category depending on sources used.  
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Tertiary literature   distilled collection of primary and secondary sources (textbooks, dictionaries, encyclopedias).  
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Etiology   the science and study of causes of illness, AKA "pathogenesis"  
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Risk factors   exposure or attribute that is associated with but not the cause of a given outcome of interest  
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Prognosis   predicted outcome of a disease or disorder, usually expressed interns of length of time until a specific outcome, such as full-recovery, limited recovery, or mortality.  
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Practice guideline   Document related to specific disease/disorder put together by expert working group w/recommendations for dx and treatment. Some use procedures of a systematic review & represent best available evidence. Other practice guidelines are expert opinion only.  
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Objective Data   information you observe or measure  
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Subjective data   patient's perceptions  
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Evidence pyramids   visual representation & system for categorizing healthcare information according to level of evidence. Top level represents highest level of evidence, those resources considered most trustworthy.  
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POEMs   Patient Oriented Evidence that Matters; high-level information sources, (print journals, online point-of-care resources), focused on a single clinical question & provide careful review of best available evidence to address the question.  
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Overweight   classified by CDC inoculates as BMI of 25.0-29.9  
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Body Mass Index (BMI)   a measure of body fat based on height & weight that applies to adult men & women  
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