Lipoproteins
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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What kind of diet decreases LDL Levels | show 🗑
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show | negative
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What decreases HDL levels? | show 🗑
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What increases HDL levels | show 🗑
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show | VLDL levels in a fasted condition
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APO C-II | show 🗑
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APO-E | show 🗑
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show | used to predict coronary heart disease
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show | VLDL-C
LDL-C
HDL-C
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show | transport dietary lipids to where they need to go
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show | fed
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show | outside the liver in the intestinal epithelial cells
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show | skeletal muscles and adipose cells
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show | Liver
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HDL donates ______ to VLDL to activate ___________. | show 🗑
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Lipoprotein synthesis induced by | show 🗑
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VLDL that leaves the liver | show 🗑
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show | IDL
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IDL becomes | show 🗑
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IDL | show 🗑
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show | liver
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IDL is recognized in the liver by | show 🗑
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Conversion of IDL to LDL (3) | show 🗑
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LDL delievers cholesterol to ____________ | show 🗑
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show | some comes from the VLDL and some comes from the HDL addition of cholesterol ester to the IDL as they become LDL
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Uptake of LDL by extra-hepatic cells occurs via | show 🗑
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De-esterified cholestol delevered by LDL inhibits synthesis of | show 🗑
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show | extra-hepatic cholesterol synthesis
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LDL utilization in extra-hepatic cells | show 🗑
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show | extra-hepatic LDL uptake
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LDL delivers cholesterol to _____________. | show 🗑
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IDL density in comparison | show 🗑
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show | down regulation of the genes for LDL receptor synthesis
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show | entry into the cell of only the amount of cholesterol needed
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show | LDL receptor-related protein
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LRP function | show 🗑
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LRP differs from LDL receptor because __________ | show 🗑
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show | decrease serum lipoprotein levels
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show | genetically defective LDL receptors occur and LDL levels become extremely high
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show | multifactorial hypercholesterolemia due to a combination of dietary, behavioral, and genetic factors
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show | decrease risk of coronary heart disease
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show | Liver
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Roles of HDL (3) | show 🗑
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show | limiting dietary cholesterol and saturated and trans fatty acids; depends on genetic make up
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show | statin drugs inhibit HMG CoA reductase
Bile and cholesterol sequestering drugs decrease bile acid reabsorption and dietyar cholesterol absorption
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show | Lp(a) thought to be a marker or predictor for cardiovascular disease
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show | post-MI
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show | atherosclerotic plaque formation
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show | 1. lipoproteins themselves are the risk factor
2. HDL and LDL are not each a specific Lipoprotein but rather occur in sub types
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show | amounts of risk of coronary heart disease
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Created by:
tjamrose
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