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MLT Boards- Chemistry (BOR)

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
        Help!  

Questions
Answers
show vanillylmandelic acid  
🗑
Which 2 conditions can "physiologically" elevated serum alkaline phosphatase?   show
🗑
The T3 resin uptake test is a measure of:   show
🗑
show a normal finding  
🗑
In the liver, bilirubin is converted to:   show
🗑
The results listed on page 120 were obtained in a creatinine clearance evaluation: The creatinine clearance in mL/min is:   show
🗑
show sharp fibrinogen peak  
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show peptide bonds  
🗑
Total iron-binding capacity measures the serum iron transporting capacity of:   show
🗑
show azobilirubin  
🗑
Absorbance (A) os a solution may be converted to percent transmittance (%T) using the formula:   show
🗑
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are both elevated in what disease?   show
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Calcium concentration in the serum is regulated by:   show
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What steroid is an adrenal cortical hormone?   show
🗑
show calculations of blood pH and total CO2 concentrations  
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In the potentiometric measurement of hydrogen ion concentration, reference electrodes that may be used include:   show
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In a spectrophotometer, light of a specific wavelength can be isolated from white light with a(n):   show
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The oslolality of a urine or serum specimen is measured by a change in the:   show
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Which of the following serum constituents is unstable if a specimen is left standing at room temperature for 8 hours before processing? cholesterol, triglyceride, creatinine, or glucose   show
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A urine screening test for porphobilinogen is positive. The MOST likely disease state is:   show
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show act as a carrier for ions  
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show iron deficiency anemia  
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show pilocarpine nitrate  
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In the sweat test, the sweating stimulant is introduced to the skin by application of:   show
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The formula for calculating serum osmolality that incorporates a correction for the water content of plasma is:   show
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show the difference between the calculated and measured osmolality values  
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Erroneous ammonia levels can be eliminated by all of the following EXCEPT: See page 124 for choices.   show
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show a. The temperature at euilibriun is a function of thenumber of particles in solution.  
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The first step to be taken when attempting to repair a piece of electronic equipment is:   show
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Most of the carbon dioxide present in blood is in the form of:   show
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show urine to serum osmolality ratio  
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How many grams of sulfosalicylic acid (MW = 254) are required to prepare 1 L of a 3% (w/v) solution?   show
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A physician suspects his patient has pancreatitis. Which test(s) would be most indicative of this disease?   show
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show mean  
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show coefficient of variation  
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show mode  
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The middle value of a data set is statistically known as the:   show
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In a specimen collected for plasma glucose analysis, sodium fluoride:   show
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show 10.0 mEq/L  
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The osmolal gap is defined as measured Osm/kg minus the calculated Osm/kg. The average osmolal gap is near:   show
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To be analysed by gas liquid chromatography, a compound must:   show
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show sodium  
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show minimize the effect of interference  
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show PO2 electrode  
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show 1 micromole/min  
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The Porter-Silber method (phemylhydrazine in alcohol and sulfuric acid) involves which part of the steroid molecule?   show
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show estrogens  
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show c. Quantitation of the label can be carried out with a spectrophotometer.  
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show acid phosphatase  
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show alpha-2 globulin and beta globulin  
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What wnzyme substrates for prostatic acid phosphatase determination results in the highest specificity?   show
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The results listes on page 128 were obtained on arterial blood: These results are most compatible with :   show
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show acute viral hepatitis  
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show placenta  
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show thiamine  
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show glycerol  
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show gamma-glutamyl transferase (GGT)  
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Refer to the illustration on page 129. This electrophoresis pattern is consistant with:   show
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show serum cortisol concentrations greater then 15 mg/dL  
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A one molal solution is equivalent to:   show
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show monoclonal gammopathy  
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show cirrhosis  
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show acute hepatitis  
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Given the results listed on page 132. This is most consistent with:   show
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Given the results listed on page 132; This is most consistant with:   show
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Which of the statements on page 132 about fluorometry are true?   show
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show reduced reagent requirements  
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show Nonlinearity after 6 minutes is due to a substrate exhaustion  
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show crush injury it the thigh  
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show inhibitor binds to the enzyme at the same site as the substrate  
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Kernicterus is an abnormal accumulation of bilirubin in:   show
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show 5  
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show distinct phenotypes by starch-gel electrophoresis  
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Which serum protein migrates with the beta-globulins on cellulose acetate at pH 8.6?   show
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Fasting serum phosphate concentration is controlled primarily by the:   show
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Serum "anion gap" is increased in patients with:   show
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show hemolytic anemia  
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The nanometer is used as a mearure of:   show
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Major actions of angiotensin II include:   show
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show myocardial infarction  
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show 0.5  
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show azobilirubin  
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show average blood glucose levels of the past 2-3 months  
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show immunofixation  
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The anion gap is useful for quality control of laboratory results for:   show
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What percentage of total serum calcium is nondiffusible protein bound?   show
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show chloride  
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What electrolyte is the cheif plasma cation whose main fumction is maintaining osmotic pressure?   show
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show calcium and phosphorus  
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show 1:100  
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show 20:1  
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The bicarbonate and carbonic acid ratio is calculated from an equation by:   show
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show bicarbonate buffer  
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A common cause of respiratory alkalosis is:   show
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show decrease in CO2 content and PCO2 with a decreased pH  
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show increase in CO2 content and PCO2 with a decreased pH  
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show 7.40  
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The normal range for the pH of arterial blood measured at 37 degree C is:   show
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show fall in pH and a rise is PCO2  
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show glass  
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In the Immunoinhibition phase of the CK-MB procedure:   show
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The conversion of glucose or other hexoses into lactate or pyruvate is called:   show
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The different water content of eryrocytes and plasma makes true glucose concentrations in whole blood a function of the:   show
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show 5 mg/dL higher  
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Which of the hemoglobins has glucose-6-phosphate on the amino-terminal valine of the beta chain?   show
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Increased concentrations of ascorbic acid inhibit chromogen production in which glucose method?   show
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The function of the major lipid components of the very low density lipoproteins (VLDL) is to transport:   show
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The most widely used support medium for electrophoretic separation os lipoproteins is:   show
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show calcium  
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Analysis of CSF for oligoclonal bands is used to screen for what disease states?   show
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60-75% of the plasma cholesterol is transported by:   show
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The major fraction of organic iodine in the circulation is in the form of:   show
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show thyroxine-binding globulin  
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show T4 by RIA  
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show 96.4-103.6  
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The extent of what measurements agree with the true value of the quantity being measured is known as:   show
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show CK  
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show decreas in NADH  
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In the Jaffe reaction, creatinine reacts with:   show
🗑
What represents the end product of purine metabolisn in humans?   show
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show have a negative charge  
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show valine, leucine, and isoleucine  
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show F  
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The parent substance in the biosynthesis of androgens and estrogens is:   show
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show testosterone  
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A 24-hour urine specimen (total volume=1136 mL) is submitted to the laboratory for quantitative urine protein. Calculate the amount of protein excreted per day. if the total protein is 52 mg/dL.   show
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show human chorionic gonadotropin (HCG)  
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show iron deficiency anemia  
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A characteristic of the Bence Jones protein that is used to distinguish if from other urinary proteins is its solubility:   show
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Which of thefollowing diagrams on page 144 is an example of a peptide bond?   show
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The principal excretory form of nitrogen is:   show
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A 45-year-old male of average height and weight was admitted to the hospital for renal function studies. He had the folloeing lab results listed on page 144. Calculate the dreatinine clearance for this patient in ml?min.   show
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In the Malloy and Evelyn methos for the determination of bilirubin, the reagent that is reacted with bilirubin to form a purple azobilirubin is:   show
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show hepatobiliary disease  
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What enzyme catalyzes the conversion of starch to glucose and maltose?   show
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show myocardial infarction  
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show amylase (AMS) and lipase (LPS)  
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What is a glycolytic enzyme that catalyzes the cleavage of fructose-1, 6-diphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate?   show
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The greatest activities of serum AST and ALT are seen in:   show
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show myocardial infarction  
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show They catalyze oxidation-reduction reactions.  
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show apoenzyme  
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The most heat labile fraction of alkaline phosphatase is obtained from:   show
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Refer ti the illustration on page 146. What id the most likely interpretation of the LD isoenzyme scan illustrated?   show
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Blood specimens for digoxin assays should be obtained between 8 hours or more after drug administration because:   show
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Bioavailability of a drug refers to the:   show
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show basic drugs  
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Zinc protoporphyrin of free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of:   show
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show cyclic antidepressants  
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show Thin layer chromatography  
🗑
show oxalacetate to malate  
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show primidone  
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show dehydration  
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show cysteine  
🗑
show thiamine  
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show A  
🗑
Scurvy is associated with deficiency of what vitamins?   show
🗑
Pellagra is associated with deficiency of what vitamin?   show
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show D  
🗑
The regulation of calcium and phosphorus metabolism is accompanied by which gland?   show
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Lithium therapy is widely used on the treatment of:   show
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show phenytoin  
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show theophylline  
🗑
A cardiac glycoside that is used in the treatment of congenital heart failure and arrhythmias by increasing the force and velocity of myocardial contraction is:   show
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show lithium  
🗑
In which disease state is conjugated bilirubin a major serum component?   show
🗑
Spectrophotometers isolate a narrow band pass by means of:   show
🗑
Refer to the illustration on page 151. The serum protein electrophoresis pattern shown was obtained on cellulose acetate at pH 8.6. Identify the serum protein fraction on the far right of the illustration.   show
🗑
The creatinine clearance (mL/min) is equal to:   show
🗑
show 4%  
🗑
What is the formula for calculating the unknown concentration based on Beer's law (A=absorbance, C=concentration)?   show
🗑
What id the formula for calculating absorbance given the percentage transmittance (%T) of a solution?   show
🗑
What if the formula for calculating the amount fo moles of a chemical?   show
🗑
How many milliliters of a 3% solution can be made if 6g of solute are available?   show
🗑
What is the formula for calculating the gram equivalent weight of a chemical?   show
🗑
What is the formula for calculating the dilution of a solution (V=volume, C=concentration)?   show
🗑
show pH = pKa + log(salt/acid)  
🗑
What is the formula for calculating a percent (w/v) solution?   show
🗑
show (standard deviation x 100)/mean  
🗑
show 128  
🗑
show sum of values/number of values  
🗑
What of the formula for calculating the molarity of a solution?   show
🗑
The results on page 154 were obtained. Given the data, calculate the patient;s creatinine clearance in mL/min.   show
🗑
show 0.83 M  
🗑
4 mL of water is added to 1 mL of serum. This represents what serum dilition?   show
🗑
show 2  
🗑
show 110  
🗑
What is the normality of a solution that contains 280 g of NaOH (MW= 40) in 2000 mL of solution?   show
🗑
A serum potassium is 19.5 mg/100 mL. This value is equal to how many mEq/L (MW of K=39)?   show
🗑
how many milliliters of 0.25 N NaOH are needed to make 100 mL of a 0.05 N solution of NaOH?   show
🗑
An arterial blood specimen submitted for blood gas analysis was abtained at 8:30 AM but was not received in th elaboratory until 11:00 AM. The technologist should:   show
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A potassium level of 6.8 m/Eq/L is obtained. Before reporting the results, the first step the technologist should take is to:   show
🗑
show heparin  
🗑
show hyperparathyroidism  
🗑
show 2.2 mg/dL  
🗑
The measurement of light scattered by particles in the sample is th eprinciple of:   show
🗑
The measurement of the amount of electricity passing between two electrodes in an electrochemical cell is the principle of:   show
🗑
show chloride  
🗑
What lipid results yould be expected to be falsely elevated on a serum specimen from a nonfasting patient?   show
🗑
Turbidity in serum suggests elevation of:   show
🗑
show glucose oxidase  
🗑
The relative migration rate of proteins on cellulose acetate is based on:   show
🗑
As part of a hyperlipidemia screening program, the results listed on page 157 were obtained on a 25-year-old woman 6 hours after eating. What is the best interpretation of these results?   show
🗑
Enzyme-multiplied immunoassay techniques (EMIT) differ from all other types of enzyme immunoassays in that:   show
🗑
Refer to the graph on page 158. A new methodology for amylase has been developed and compared with the existing method as illistrated in the graph. the new method can be described as:   show
🗑
a 48-year-old woman with mild jaundice has the serum results lidted on page 158. What sources most contributes to the patient's serum alkaline phosphatase activity?   show
🗑
show PCO2  
🗑
show activity of one ion much more thatn other ions present  
🗑
An automated method for measuring chloride that generates silver ions in the reaction is:   show
🗑
A patient's values are as listed on page 159. What is the patient's free thyroxine index?   show
🗑
A person suspected of having metabolic alkalosis would have what laboratory findings?   show
🗑
show normal pregnancy  
🗑
show dirty electrodes  
🗑
show 180  
🗑
What is most likely to be ordered in addition to serum calcium to determine the cause of tetany?   show
🗑
A 9-month-old boy from Israel has gradually lost the ability to sit up & developes seizures. he has an increased amount of a phospholipid called GM2-ganglioside in his neurons, & he lacks the enzyme hexosaminidase A in his leukocytes. The findings suggest   show
🗑
An adult diabetic with renal complications has the results listed on page 161. On the basis of these results, the calculated serum osmolality is:   show
🗑
the formation of estriol in a pregnant woman is dependent on:   show
🗑
show elevated PO2, decreased PCO2, and elevated pH  
🗑
Magnesium carbonate is added in an iron binding capacity determination in order to:   show
🗑
An elevated serum iron with normal iron binding capacity is most likely associated with:   show
🗑
A patient's blood was drawn at 8am for a serum iron determination. The result was 85 ug/dL. a repeat specimen was drawn at 8pm; the serum was stored at 4 degrees C & run the next morning. The result was 40ug/dL. these results are most likely due to:   show
🗑
show BUN increased  
🗑
show intrinsic factor  
🗑
Refer to the illustration on page 163. The above sybol posted in an area would indicate what hazard?   show
🗑
show low pH  
🗑
what battery of tests is most useful in evaluating an anion gap of 22mEq/L?   show
🗑
show lower than in adults  
🗑
Oligoclonal bands are present on electrophoresis of concentrated CSF and also concurrently tested serum of the same patient. the porper interpretation is:   show
🗑
show inclusion os nonsmokers and smokers in the study population  
🗑
show pH, PCo2, and PO2  
🗑
In the assay of lactate dehydrogenase (LD), the reactionis dependent on which of the following coenzyme systems?   show
🗑
show glomerular filtration rate  
🗑
show 100 nmol/L  
🗑
The chemical composition of HDL-cholesterol corresponds to:   show
🗑
The principle of the tablet test for bilirubin in urine or feces is:   show
🗑
show 975.6  
🗑
If 0.5 mL of a 1:300 dilution contains 1 antigenic unit, 2 antigenic units would be contained in 0.5 mL of a dilution of:   show
🗑
show pH=6.1+log[(25-1.2)/(1.2)]  
🗑
Blood was collected in a serum separator tube from a patient who had been fasting since midnight. The time of collection was 7:00 AM. The laboratory test that should be re-collected is:   show
🗑
the cellulose acetate electrophoresis at pH 8.6 of serum proteins will show an order of migration beginning with the fastest migration as follows:   show
🗑
show depression  
🗑
show iron hemachromatosis  
🗑
show exposure to carbon monoxide  
🗑
show high TCO2, increased HCO3  
🗑
For the past 3 weeks serum estriol levels in a pregnant woman have been steadily increasing. This is consistant with:   show
🗑
show to prevent phosphate interference  
🗑
A patient has the thyroid profile listed on page 167. This patient most probably:   show
🗑
show 5.50-6.10 mg/dL  
🗑
show has 200 times the affinity of oxygen for hemoglobin binding dites  
🗑
show monitoring the course of a known cancer  
🗑
Estrogen and progesterone recptor assays are useful in assessing prognosis in what?   show
🗑
A chemiluminescent EIA:   show
🗑
The selectivity of an ion-selective electrode is determined by the:   show
🗑
Valinomycin enhances the selectivity of the electrode used to quanitiate:   show
🗑
A 45-year-old woman has a fasting serum glucose concentration of 95 mg/dL and a 2-hour postprandial glucose cincentration of 105 mg/dL. The statement that best describes this patient's fasting serum glucose concentration is:   show
🗑
show effluent line obstructed  
🗑
An infant with diarrhea is being evaluated for a carbohydrate intolerance. His stool yields a positive copper reduction test and a pH of 5.0. It should be concluded that:   show
🗑
In a centrifugal analyzer, centrifugal force is used to:   show
🗑
show chylomicrons and very-low-density lipoproteins (VLDL)  
🗑
Factor that contribute to a PCO2 electrode's requiring 60-100 seconds to reach equilibrium include the:   show
🗑
In which of the following conditions would a NORMAL level of creatine kinase be found? acute mycardial infarct, hepatitis, progressive muscular dystrophy, intramuscular injection   show
🗑
show the ionization of the carboxyl groups, yielding a net negative charge  
🗑
show correct for variations in light source intensity  
🗑
Gel filtration chromatography is used to separate:   show
🗑
show exchange of amino and keto groups between alpha-amino and alpha-keto acids  
🗑
Ninety percent of the copper present in plasma is bound to:   show
🗑
In lipoprotein phenotyping. chylomicrons are present in the plasma of persons with what lipoprotein phenotypes?   show
🗑
A 600 mg/dL glucose solution is diluted 1:30. The concentration of the final solution in mg/dL is:   show
🗑
Monitoring long-term glucose control in patients with adult onset diabetes mellitus can best be accomplished by measuring:   show
🗑
The disease most often associated with elevations of lactate dehydrogenase isoenzymes 4 and 5 on electrophoresis is:   show
🗑
The following five sodium control values (mEq/L) were abtained: 140, 135, 138, 140, 142 Calculate the coefficient of variation.   show
🗑
A spectrophotometer is being considered for purchase by a small laboratory. what specifications reflects the spectral purity of the instrument?   show
🗑
An LD1 greater than LD2 fraction of lactic dehydrogenase is most often associated with:   show
🗑
How many milliliters of 30% bovine albumin are needed to make 6 mL of a 10% albumin solution?   show
🗑
show thymolphthalein monophosphate  
🗑
show warmed to 37 degree C and mixed thoroughly  
🗑
show changes when it turns pink  
🗑
A serum sample was assayed for bilirubin at 10 AM and the result was 12 mg/dL. The same sample was retested at 3PM. The result mow is 8 mg/dL. The most likely explanation for this descrepancy is:   show
🗑
To prepare a physiologic saline solution, dissolve:   show
🗑
A chemistry assay utilizes a bichromatic analysis. This means that absorbance readings are taken at:   show
🗑
Serial bilirubin determinations are charted on page with the best explanation for the results due to:   show
🗑
Infamilial hypercholesterolemia, tha hallmark finding is an elevation of:   show
🗑
show glucose tolerance test  
🗑
The most consistent analytical error involves in the routine determination of HDL-cholesterol is caused by:   show
🗑
Nephelometers measure light:   show
🗑
show urobilin  
🗑
Premature atherosclerosis can occur when what becomes elevated?   show
🗑
show total cholesterol and HDL-cholesterol  
🗑
High levels of what lipoprotein class are associated with decreased risk of accelerated atherosclerosis?   show
🗑
show <=45 mg/dL  
🗑
show separation of iron from transferrin  
🗑
show peroxidase-like activity of hemoglobin  
🗑
show correct for variations in flame and atomizer characteristics  
🗑
show 340 nm  
🗑
show two thirds of the standard  
🗑
Aspartate aminotransterase (AST) is characteristically elevated in diseases of the :   show
🗑
show creatine kinase  
🗑
show maintain colloidal osmotic pressure  
🗑
Most chemical meethods for setermining total protein utilize what reactions?   show
🗑
The mean value of a series of hemoglobin controls was found to be 15.2 g.mL, and the standard deviation was calculated at 0.20. Acceptable control range for the laboratory is +/- 2 standard deviations. What represents the allowable limits for the control?   show
🗑
show an inflammatory process  
🗑
show differential solubility  
🗑
The T3-uptake test is based on:   show
🗑
The most specific method for the assay of glucose utilizes:   show
🗑
The enzyme present in almost all tissues that may be separated by electrophoresis into five components is:   show
🗑
show 95 %  
🗑
show precision  
🗑
When 0.25 mL is diluted to 20 mL, the resultion dilution is:   show
🗑
show accuracy  
🗑
show bilirubin  
🗑
show standard  
🗑
show 10  
🗑
In performing a spinal fluid protein determination, the specimen is diluted 1 part spinal fluid to 3 parts saline to obtain a result low enough to measure. To calculate the protein concentration the results must be:   show
🗑
In order to prepare 100 mL of 15 mg/dL BUN working standard from a stock standard containing 500 mg/dL of urea nitrogen, the amount of stock solution used is:   show
🗑
In monitoring glomerular function, what test has the highest sensitivity?   show
🗑
An automated CK assay gives a reading that is above the limits of linearity. A dilution of the serum sample is made by adding 1 mL of serum to 9 mL of water. The instrument now reads 350 U/L. The correct report on the undiluted serum should be:   show
🗑
Blood received on the laboratory for blood gas analysis must meet what requirements?   show
🗑
An electrode has a silver/silver chloride anode & a platinum wire cathode. It is suspended in KCl solution & separated from the blood to be analysed by a selectively permeable membrane. Such an electrode is used to measure what?   show
🗑
show CO2  
🗑
A thick white turbid specimen was received in the lab labeled as pericardial fluid. A microscopic examination was performed, and the differential included 90% PMN's. The fluid is:   show
🗑
In the assay of lactate dehydrogenase, what product is actually measured?   show
🗑
show 40  
🗑
Bromcresol pruple at a pH of 5.2 is used in a colorimetric method to measure:   show
🗑
In spectrophotometry, the devise that allows for a narrow band of wavelengths is the:   show
🗑
show 1.2%  
🗑
If a fasting glucose were 90 mg/dL, which of the following 2-hour postprandial glucose results would most closely represent normal glucose metabolism? 55, 100, 180, or 260 mg/dL   show
🗑
show specimen had a prolonged exposure to light  
🗑
In flame emission photometry, an excited arbital electron returns to ground state and emits:   show
🗑
The first procedure to be followed if the blood gas instrument is out of control for all parameters is:   show
🗑
What method for quantitation of high-density lipoprotein is most suited for clinical lab use?   show
🗑
Urobilinogen is formed in the:   show
🗑
show 50  
🗑
Upon completion of a run of cholesterol tests, the technician recognizes that the controls are not within the 2 standard deviations confidence range. What is the appropriate course of action?   show
🗑
A technician is asked by the supervisor to prepare a standard solution solution from the stock standard. What is the glassware of choice for this solution.   show
🗑
Slight hemolysis can cause erroneous laboratory results in which serum analyte?   show
🗑
show 20 mL  
🗑
A stool specimen that appears black and tarry should be tested toe the presence of:   show
🗑
show allow indirect bilirubin to react with color reagent  
🗑
To prepare 25 mL of 3% acetic acid, how much glacial acid is needed?   show
🗑
show 9.0  
🗑
show measure the total volume  
🗑
show 0.2  
🗑
What is the first step in preparing a spectrophotometer for an assay?   show
🗑
A 25-year-old man became nauseated and vomited 90 minutes agter receiving a standard 75-g charbohydrate dose for an oral glucose tolerance test. The best course of action is:   show
🗑
show specimen hemolysis  
🗑
show CK-MB  
🗑
Cerebrospinal fluid for glucose assay should be:   show
🗑
The preparation of a patient for standard glucose tolerance testing should include:   show
🗑
Measurement of the serum acid phosphatase is used to detect neoplastic disease of the:   show
🗑
A serum sample demonstrates an elevated result when tested with the Jaffe reaction. This indicates:   show
🗑
An increase in serum acetone is indicative of a defect in the metabolism of:   show
🗑
show 1.2 mL  
🗑
show 6.0 mL  
🗑
show all values are consistent with a normal healthy individual  
🗑
show wavelength of radiant energy  
🗑
show 1.1 mg/dL  
🗑
The ability of a procedure to measure only the component(s) it claims to measure is called:   show
🗑
The most widley used methods for bilirubin measurement are those based on the:   show
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show repeat the test using freshly drawn serum  
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show adding an acid stabilizer  
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show aacid phosphatase with freshly drawn serum  
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When performing a manuel protein analysis on a xanthochromic spinal fluid, the technician should:   show
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Which of the following 2-hour postprandial glucose values demonstrates unequivocal hyperglycemia diagnostic for diabetes mellitus? 160, 170, 180, or 200 mg/dL   show
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show 8-12 weeks  
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show spun,sepatared, iced, and tested immediately  
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show lipase  
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Created by: dayzemai
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