Question | Answer |
deciduous teeth | milk or baby teeth |
The outer surface of the tooth root is covered by __. | cementum - calcified CT |
What anchors tooth in bony alveolus of jaw? | Peridontal ligament |
Bonelike material underlying enamel cap & makes up bulk of tooth. | Dentin |
Dental caries | cavities |
Calculus | tartar |
Histology of pharyngeal wall | Stratified squamous w/mucus-producing glands |
There are 2 __ layers in pharyngeal wall. | skeletal muscle |
How long is esophagus? | 25 cm (10 inches) long |
How does epithelium change abruptly at esophagus-stomach junction. | Esophageal mucosa change from nonkeratinized stratified squamous to simple columnar epithelum which is specialized for secretion. |
Submucosa's esophageal glands secrete? | Mucus to grease the esophageal walls to aid food passage. |
The outermost layer of esophagus. | Adventitia (Fibrous CT) |
Name 2 digestive system structures whose only role is food propulsion. | Pharynx & esophagus |
deglutition | Swallowing - involves 22 separate muscle groups - buccal phase & pharyngeal-esophageal phase. |
Which phase of deglutition is voluntary? | buccal phase |
The pharyngeal-esophageal phase of deflutition is controlled by __. | Swallowing center in brainstem - medulla & lower pons - transmitted through vagus nerves. |
What structural modification of stomach tunic allows mechanical digestion? | Muscularis externa has 3rd layer of smooth muscle to churn food - runs obliquely. |
Size of adult stomach | 15-25 cm (6-10 inches) 50 ml empty - 1 gallon full |
What part of stomach is continuous with duodenum. | Pylerus |
Lining of stomach | Simple columnar epithelium w/goblet cells that produce alkaline mucus - makes a bicarbonate-rich fluid layer. |
Mucous neck cells of stomach | Produce thin mucus - acidic |
Parietal cells of stomach | Secrete HCl & intrinsic factor - have microvilli |
Intrinsic factor is? | Glycoprotein for B12 absorption in small intestine, but produced in stomach. |
Ph of stomach | 1.5 - 3.5 |
Chief cells of stomach | Produce pepsinogen (inactive) - activated by HCl & becomes pepsin - positive feedback process. |
Enteroendocrine cells of stomach | Release chemical messengers - histamine, gastrin, serotonin, somatostatin |
What barrier protects stomach from self-digestion? | Gel-like mucosal barrier - (1) bicarbonate-rich mucus, (2) tight junctions, (3) stem cells that divide & replace quickly. |
gastritis | inflammation of stomach wall due to anything that breaches mucosal barrier |
Name some H2-receptor blocker drugs | Tagmet & Zantac |
Vagus nerve does what what with stomach. | Stimulates secretory activity of virtually all of its glands. |
Which hormone controls gastric secretion? | Gastrin - enzymes, HCL |
3 phases of gastric secretion | Cephalic (reflex), gastric, & intestinal - all may be occuring at same time. |
Cephalic reflex (Phase 1) | Conditioned reflex - occurs before food enters stomach - triggered by senses, prepares stomach - suppressed when emotinally depressed. |
Gastric Phase (Phase 2) | In stomach - 3-4 hours long - distension & gastrin are stimulus. |
G cells | Gastrin - secreting enteroendocrine cells. |
Highly acidic gastric contents __ gastrin secretion. | Inhibit |
Protein __ pH in stomach | raises - stimulates gastrin & HCl release |
HCl secretion is stimulated by which 3 chemicals? | ACh, gastrin, & histamine (by enterochromaffin-like cells) - all 3 combined causes HCl to pour forth. |
Blood draining from stomach is more __ than blood serving it. | alkaline - phenomenon called alkaline tide. |
Intestinal Phase (3) | 2 components - excitatory & inhibitory - excitatory - gastric gland in duodendum produce intestinal gastrin: inhibitory - enterogastric reflex that puts on "breaks" to protect small intestine from acidity. |
Enterogastric reflex | release is inhibited. |
Plasticity | Smooth muscle's ability to stretch without greatly increasing tension & contracts expulsively. |
What sets rate of stomach's peristalic waves? | Pacemaker cells in longitudinal small muscle layers called interstitial cells of Cajal - don't initiate beat, neural does. |
Basic electrical rhythm (BER) | Cyclic slow waves of stomach due to pacemaker interstitial cells of Cajal. |
Stomach usually empties completely within __ hours. | 4 |
emesis | vomiting |
Where is emetic center located? | Controls vomiting - in medulla |