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Renal Disorder/Burns

Normal GFR 120-125 mL/min
Manifestations of Polycystic Kidney Disease Flank pain, hematuria, proteinuria, polyuria, nocturia, UTI, calculi, HTN, palpable kidneys
Diagnostic testing of PKD Ultrasound (procedure of choice), IVP, CT scan
PKD Management Fld. intake of at least 2000 mL/day, ACE inhibitors, teach measures to prevent UTIs, avoid nephrotoxic drugs, dialysis or transplant eventually required.
Glomerular disorders Leading cause of chronic renal failure, a primary or secondary disorder, filtration is disrupted, membrane becomes more permeable to plasma proteins and blood cells.
Manifestations of glomerular disorders Hematuria, proteinuria (best indicator of injury), hypoalbuminemia, edema, azotemia r/t falling GFR, HTN, oliguria.
Acute Glomerulonephritis Inflammation of glomerular membrane, poststreptococal is most common form (APSGN), antibody complexes trapped in glomerular membrane leads to inflammation
Manifestations of Acute Glomerulonephritis Abrupt onset of proteinuria, hematuria, salt & water retention, azotemia, cola-colored urine, periorbital & dependent edema, fatigue, anorexia, N&V. Less apparent in older adults.
Nephrotic syndrome Group of clinical findings. Massive proteinuria, hypoalbuminemia, hyperlipidemia, & edema. Increased risk of atherosclerosis & clots. Good prognosis in children, less optimistic in adults.
Specific Gravity 1.001-1.030
pH 4.5-8.0
BUN 5-20
Creatinine 0.5-1.2
Hgb 12-17
Hct 36-54%
Chloride 97-107
Phosphate 2.5-4.5
Sodium 135-145
Potassium 3.5-5.0
Calcium 8.6-10.0
Created by: fulk_90