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Physiology !!!
Transmitters and Receptors
| Question | Answer |
|---|---|
| Fibers (or synapses) are | Adrenegeric or cholineric |
| Most postgang sympathetic fibers adrenegeric | Rest (including all pregang sympathetic, all parasympathetic, and a few postgang sympathetic) are cholinergic |
| Cholingeric receptors are | 1.muscarinic 2. nicotinic |
| What blocks muscarinic receptors? | atropine |
| muscarinic | (at postgang effectors for all parasympathetic and those few cholinergic sympathetic) |
| At all ganglionic synapses (ends of pregang fibers) Also type at skeletal muscle neuromuscular junctions (Curare blocks these) | Nicotinic |
| Adrenergic receptors are | Alpha(a) or beta(b) |
| Alpha(a) causes vasoconstriction in | peripheral blood vessels |
| Beta(b) causes | Vasodilation |
| Norepinephrine | Mainly A |
| Epinephrine | A&B |
| Adrenergic Receptor Subtypes A1 & A2 | Both cause decrease in cAMP production; A1 may cause increase in intracellular Ca++ - usually excitatory |
| Adrenergic Receptor Subtypes B1 & B2 | Both increase cAMP production - usually inhibitory |