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Fred Antibiotics

QuestionAnswer
Penicillin Syphilis - Treponema pallidum, coiled spirochette Streptococcus, Clostridium
Aminopenicillins: Amoxicillin, Ampicillin (IV) Streptococcal Pharyngitis - Streptococcus pyogenes (Group A Strep) haemophilus, E. coli, proteus
Penicillinase-resistant Penicillins: Nafcillin (IV), Oxacillin (IV), Dicloxacillin (PO) Methicillin sensitive staphylococcus aureus- gram positive, catalyst positive, coagulates
β-lactamase Inhibitors: Ampicillin-sulbactam (Unasyn - IV) Amoxicillin-clavulanic acid (Augmentin - PO) Piperacillin-tazobactam (Zosyn - IV) Pseudomonas aeruginosa: Gram negative, grape smell - Uncommon for humans to be carriers except in hospital, or immuno compromised Primarily opportunistic infections
Cephalosporins: Cefazolin (IV)Cephalexin (PO)Cefoxitin (IV)Ceftriaxone (IV/IM)Cefepime (IV) Streptococcus pneumoniae - meningitis (over 65)
Monobactams: Aztreonam (IV) Gram negatives
Carbapenems: doripenem Very broad spectrum of activity against gram positives and gram negatives β-lactamase resistant Do not cover MRSA, Enterocococcus faecium, or C. difficile Ertapenem, imipenem, doripenem, meropenem (all IV) Common adverse effects are nausea,
Vancomycin Only active against gram positives, including MRSA Binds to D-Ala-D-Ala to inhibit transglycosylases Less effective than β-lactams for susceptible organisms IV except when used to treat C. difficile diarrhea (PO)methicillin resistant staphylococcus aur
Daptomycin Active against gram positives including vancomycin resistant strains of enterococci and staph aureus
Trimethoprim-Sulfamethoxazole (TMP-SMX) TMPS - streptococcus pneumonia , gram negatives that cause bacteria,UTI, pneumocystis carini pneumonia (AIDS)
Quinolones/Flueroquinolones: nalidixic acid, norfloxacin, ciprofloxacin, levofloxacin, moxifloxacin Gram negative coverage, Long QT and cartilage
Rifamycins: rifampin, rifabutin, rifaximin RNA inhibitors, Rifampin prophylactic therapy against Neisseria meningitidis Used in four drug therapy to treat Mycobacterium tuberculosis
Pegylated Interferon-alpha + ribavirin HCV
Created by: 841836
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