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DIT viruses
| Question | Answer |
|---|---|
| erythema infectiosum (AKA fifth disease) | Parvovirus B19 |
| Heterophil-positive mononucleosis | EBV |
| Can cause conjunctivitis or diarrhea | Adenovirus |
| Enlarged cell with owl's eye inclusions | CMV |
| Identified with a Pap smear | HPV (16,18) |
| Milkmaid's blisters | cowpox |
| Burkitt's lymphoma and nasopharyngeal carcinoma | EBV |
| Gingivostomatitis | HSV1 |
| Hides in sensory ganglia of S2 and S3 | HSV2 |
| Hades in trigeminal ganglia | HSV1 |
| Hides in dorsal root ganglia | VSV |
| viral family of FC virus | polyomavirus |
| downey cells | EBV |
| human progressive multifocal leukoencephalopathy | JC virus |
| oral hairy leukoplakia | EBV |
| multinucleate giant cells on tzanck test | HSV1,2, VSV |
| Only DNA virus that is not double stranded | Parvovirus |
| Roseola | HHV-6 |
| Heterophil negative mononucleosis | CMV |
| Hand, foot, and mouth disease | coxsackie |
| Break bone fever | Dengue = flavivirus |
| Characteristic barking seal cough | croup = paramyxovirus |
| African hemorrhagic fever | filovirus |
| common cold | coronavirus |
| fever, jaundice, black vomit | yellow fever = flavivirus |
| childhood diarrhea in winter months | rotavirus |
| asthma sounding infection in infants (esp. premies) | RSV = paramyxovirus |
| Meningitis in summer months | Echovirus |
| Tourniquet test helps diagnose hemorrhagic disease | Dengue/flavivirus |
| Infects motor neurons of the anterior horn | Poliovirus and west nile virus |
| 45 yo male w/ squamos cell carcinoma of penis had exposure to what virus? | HPV (16,18) |
| 20yo colleg student with lymphadenopathy, fever, and hepatosplenomegaly. His serum agglutinates sheep RBCs. what cell type is infected | B cells |
| How does rabie virus travel through the CNS so that it can cause fatal encephalitis with seizures? | retrograde up nerve axons |
| What is the characteristic shape of the rabies virus? | bullet shaped capsid |
| a/w Kaposi's sarcoma | lymphoangiogenic GFs/CKs: TNFalpha, IL-6, PDGF |
| diagnosis of west nile virus | serology for IgM anti-WNV abs |
| laryngo-tracheo-bronchitis | parainfluenza/croup |
| leading cause of hospitalization in kids less than 4 yo | parainfluenza/croup |
| brassy cough | RSV bronchiolitis |
| Pavlivizumab | monoclonal RSV Ig |
| 2 most common causes of common cold | rhinovirus, coronavirus |
| aspetic meningitis | echovirus, coxsakie virus |
| what causes a steeple sign on x-ray? | parainfluenza/croup |
| what causes a thumb sign on x-ray | epiglottitis - Hib |
| What is the treatment for HSV, VZV, and EBV | acyclovir |
| what is the tx for CMV | gangciclovir |
| what is the tx for CMV retinits | foscarnet |
| What is IFN-alpha used for | HCV, HBV, kaposi sarcoma |
| inhibits CMV DNA polymerase | gangciclovir and foscarnet |
| used in tx for chronic hep C | IFNalpha, ribavirin |
| blocks viral penetration and uncoating | amantadine, ramantidine |
| treats both influenza A and B | oseltamivir, zanamivir |
| second line for CMV retitinis | Foscarnet |
| -sAg, +sAb, +cAb | recovery |
| -sAg, -sAb, +cAb | window period |
| +sAg, -sAb, +IgM cAb | recent/acute infxn |
| +sAg, -sAb, +IgG cAb | chronic infxn |
| -sAg, +sAb, -cAb | immunized |