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DNA replication BF
| Question | Answer |
|---|---|
| What is the structure of DNA? | Double helix |
| How are mutations spread? | Parent cells give mutations to daughter cells |
| What is DNA polymerase? | A hereditary disorder characterized by familial multiple tumors and caused by a mutation in the p53 gene |
| Replication | the duplication of DNA |
| Helicase | splits 2 strands of DNA by splitting hydrogen bonds |
| Single stranded binding proteins | binds to outside of single strands to keep strong and safe and to keep strands apart |
| Primerase | makes RNA primer |
| RNA Primer | gives polymerase a way to attatch and gives 3 prime end to attatch to the 5 prime end; gives stability |
| 5 prime end of nucleotide | how one nucleotide connects to the next |
| 3 prime end of nucleotide | how one nucleotide connects to the next |
| Orgin of replication | site where replication bubble begins |
| Replication bubble | splits DNA from replication from orgin of replication |
| Replication fork | part of replication bubble that has not split yet |
| Leading strand | new strand that grows towards the replication fork |
| Lagging strand | new strand that grows away from replication fork |
| Ligase | joins Okazaki fragments |
| Telomere | ends of chromosomes |
| Telomerease | an enzyme that adds DNA sequence repeats |
| Transcription | transcribes DNA into RNA, creats an RNA strand complimentary to the DNA |
| Promoter | specific sequence that is similar in all genes |
| RNA Polymerase | binds to promoter, stops moving when reached TAC |
| Start Triplet TAC | when RNA polymerase starts making RNA, on the DNA strand |
| Start Codon AUG | when RNA polymerase starts making RNA, on the RNA strand |
| 5 prime cap | made of guanine, on start end of RNA |
| 3 prime Poly A tail | made of adenine, it's on stop end of RNA |