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PharmGU
Drugs r/t BPH and Erectile Dysfunction
| Question | Answer |
|---|---|
| What is the result of PDE5 inhibition? | A long and harder erection. |
| Which drug is used for erectile dysfunction and pulmonary HTN? | Viagra (sildenafil) |
| Persistent and painful erection of the penis. Also an AE of Viagra. | Priapism |
| Name two rare AE of the Viagra. | Nonarteritic ischemic optic neruopathy. Sudden hearing loss. |
| Pts taking viagra should not stand up quickly. T or F? | True. Hypotension is a SE |
| Headache and flushing are potential AE of which erectile dysfunction drug? | Viagra (sildenafil) |
| Which of these drugs is not contraindicated with Viagra? Nitrites, Diuretics, a-blockers, CYP3A4 drugs? | Diuretics. The other three are contraindicated. |
| Cialis should only be taken when a pt has the need for an erection. T or F? | False. Take daily. |
| Which erectile dysfunction drug causes QT interval prolongation w/antidysrhythmic drugs? Viagra, Levitra, Cialis, or Avodart? | Levitra |
| Excessive growth of epithelial (gradular) cells is which type of BPH? Mechanical or Dynamic? | Mechanical |
| Exessive growth of smooth muscle cells is which type of BPH? Mechanical or Dynamic? | Dynamic |
| This type of BPH can have s/s without an enlarged prostate. Mechanical or Dynamic | Dynamic |
| 5-alpha reductase inhibitors are used for which type of BPH? Mechanical or Dynamic? | Mechanical |
| Alpha-1 adrenergic antagonists are used for which type of BPH? Mechanical or Dynamic? | Dynamic |
| finasteride (Proscar) and dutasteride (Avodart) are used for which type of BPH? Mechanical or Dynamic? | Mechanical |
| Proscar and Avodart are known as which classification of drug? | 5-alpha reductase inhibitors |
| Pt states they have been on Avodart for 4 months now and still have s/s of BPH. How should the nurse respond? | It may take 6-12 months to experience full effects. |
| Which lab levels should be drawn when taking Proscar? Should they be lower or higher than before drug started? | PSA. They should be lower. |
| Might pts who are on Proscar need a prescription for an erectile dysfunction as well? Why or why not? | Yes. An AE of Proscar/Avodart is dec. ejaculate vol. and libido. |
| A male pt on Avodart complains of pain, swelling, and growth in his pectoral area. How should the nurse respond? | Gynecomastia is an AE of Avodart |
| Women should avoid sexual intercourse with men taking Avodart if they are of child bearing age or pregnant? T or F? | True. Avodart is Preg X drug. |
| This BPH drug relaxes smooth muscle in the bladder neck, prostate capsule and prostatic urethra. | Alpha 1 Adrenergic Antagonists (Flomax) |
| This BPH drug is useful in symptom management with MILD enlargement | A-1 Adrenergic Ant. |
| silodosin (Rapaflo) and tamsulsosin (Flomax) are selective or nonselective? | Selective |
| Abnormal ejaculation is more an AE of selective or nonselective drugs? | Selective |
| "osins" such as alfuzosin are selective or nonselective drugs? | Nonselective |
| What is a primary nsg dx for "osin" drugs? Risk for infection, Risk for falls, Risk for disturbed body image, Risk for aspiration? | Risk for falls. AE of osins include Hypotension, dizziness, and fainting. |
| Nasal congestion is a common AE of selective or nonselective drugs? | Nonselective |
| Which of these drugs is most contraindicated with doxazosin? lasix, metformin, insulin, gabapentin? | Lasix. These two drugs combined can severly drop blood pressure. |
| What is an herbal preparation commonly used with BPH? | Saw Palmetto |
| Since Saw Palmetto is a herbal supplement, it is safe in use with pregnancy. T or F? | False |