Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Chemotherapy
Chemotherapy Drugs and Common Reactions
| Question | Answer |
|---|---|
| These antineoplastic drugs interfere with DNA and prevent nucleic acid from completing cell division | Alkylating agents (Cytoxan) |
| This is the most widely used class of antineoplastics | Alkylating agents (Cytoxan) |
| This is an adverse rxn specific to Alkylating agents such as Cytoxan | Hemmorhagic cystitis |
| This is given to inactivate urotoxic metabolites in the bladder | MESNA |
| These antineoplastic drugs cause cell death or slowed growth | Antimetabolites (methotrexate) |
| This antimetabolite blocks the synthesis of folic acid | Methotrexate |
| These two drugs are used for diagnoses other than Cancer | Cytoxan and Methotrexate |
| Pts taking this antineoplastic drug should increase fluid intake and hydrate well to prevent renal side effects such as HC | Cytoxan |
| Pneumotitis and fibrosis are common adverse rxns to this antineoplastic drug | Methotrexate |
| This side effect of methotrexate includes renal cellular death | Acute Tubular Necrosis |
| ATN in use with methotrexat should be treated with | IVF containing sodium bicarb to alkalinize urine |
| BM toxicity, oral and GI ulceration, and bowel perforation are common adverse rxns with this dose limiting drug | methotrexate |
| Substances from bacteria that can kill cancer cells | Antitumor Antibiotics |
| This IV drug often appears red | doxorubicin (Adriamycin) |
| This form of administration involves small lipid sacs that open and release when they reach the cancer cells | Liposomal administration |
| Liposomal administration is specifically used for which antineoplastic drug? | doxorubicin (Adriamycin) |
| Cardiotoxicity and Angioedema are side effects specific to this antineoplastic drug | doxorubicin (Adriamycin) |
| This category of antineoplastic drugs affect cell division | Natural products |
| This drug is specific to the M-phase and administered IV | Vincristine (Oncovin) |
| Nervous system toxicity is specific to this dose limiting drug | Vincristine (Oncovin) |
| Numbness, tingliign, muscular weakness, and loss of reflexes are associatedd with side effects of this system | Nervous system (Neuropathy) |
| Severe constipation is specific to this antineoplastic drug | Vincristine (Oncovin) |
| Allergic rxns are HUGE with this antineoplastic drug | Vincristine (Oncovin) |
| An added benefit on this antineoplastic category is that they are BM sparing | Natural products |
| These slow the growth of hormon-dependent TUMORS by blocking substances essential for growth | Hormone/Hormone antagonists |
| Gynecomastia and Hirsutism are adverse rxns of which type of hormone therapy | Sex hormone therapy |
| These block estrogen receptors on breast cancer cells, but have estrogen effects on non-breast cells as well. | SERMs Tamoxifen (Nolvadex) |
| Added benefits of this drug include improved bone density and improved lipid profiles | Tamoxifen (Nolvadex) SERM |
| Drug of choice for metastatic breast cancer | Tamoxifen (Nolvadex) SERM |
| Given prophylactically to decrease breast cancer risk | Tamoxifen (Nolvadex) SERM |
| This should be given with food or milk to decrease GI stress | Tamoxifen (Nolvadex) SERM |
| Potentially fatal effects of this drug include DVTs and endometrial cancer | Tamoxifen (Nolvadex) SERM |
| These stimulate the body's immune system to fight against tumor cells | BRMs |
| These attack only one specific type of tumor cell. These cells MUST posses theh specific protein receptor | Monoclonal antibodies |
| This monoclonal antibody is used against breast cancer | Herceptin |
| These are used in transplant pts to reduce immune response | Monoclonal antibodies |
| These are used in autoimmune diseases (RA, lupus) and asthma to suppress the immune system | Monoclonal antibodies |
| Used in lymphoma, HER2 receptor positive cancers (Breast), HER1, and Leukemia | Monoclona antibodies |
| Increases killing potential of chemo | Monoclonal antibodies |
| Inhibit angiogenesis | Monoclonal antibodies |
| Because cells can repair in this stage, drugs are not as effective | G0 phase |
| An example of a high growth fraction cancer | lymphoma |
| Example of a low growth fraction cancer | Solid tumors as in breasts or lung cancer |
| Course of chemotherapy includes (think frequency in wks) | Every 3 weeks with 6-12 treatments at a time |
| This antineoplastic drug is HIGHLY does specific | Doxorubicin (Adriamycin) |
| What color are chemo bags? | Yellow |
| PPE employed in preparation and administration of Chemo | Special gloves, gown, and mask |
| How long should excretia precautions be employed | 48 hours |
| Excretia precautions include... | Wear gloves for all body fluids, double flush toilet, No body fluids in trash!!! |
| Onset of emetogenic effects with chemo drugs | 1-2 days (Premedicate) |
| What is the low point of BM suppression referred to? | Nadir |
| Anemia, thrombocytopenia, and neutropenia are all effects of | Bone marrow suppresion |
| This effect of chemo can result in high risk for infections | Neutropenia |
| Absolute Neutrophil Count <500 | Neutropenia |
| This drug stimulates neutrophil production by BM | Filgrastim (Neupogen) |
| This drug should not be given within 24 hrs of chemo | Filgrastim (Neupogen) |
| Bone pain is a common side effect of this drug and contraindicated in peopel with bone cancer. | Filgrastim (Neupogen) |
| Chlorohexadine gluconate (Peridex) are used to treat which side effect of chemo | Mucositis |
| Half/half saline peroxide mixture | Mucositis |
| This effect of chemo is alleviated by the swish and spit regimen | Mucositis |
| Viscous Lidocain is used with which side effect of chemo | Musocitis |
| This drug is used to "rescue normal cells" | Folinic Acid |
Created by:
Blitzkid22
Popular Nursing sets