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Thyroid Drugs
Synthroid, PTU, Tapazole, Iodide 131
| Question | Answer |
|---|---|
| Synthetic form of T4 | Synthroid (levothyroxine) |
| Take 30 min before breakfast. | Synthroid |
| This drug must be taken daily for life | Synthroid |
| Dosing started low and increased | Synthroid |
| Monitor TSH. High w/Hypo | Synthroid |
| Narrow Tx range | Synthroid |
| Cardiovascular issues can be uncovered with tx with this drug | Synthroid |
| Drug interactions for synthroid include... | Cholesterol drugs in the GI. Iron, calcium, Digoxin, Insulin, fiber, walnuts, and soybean flour. WARFARIN. Catecholemines. |
| Prevents conversion of T4 to T3 Interferes with T4 & T3 synthesis | PTU |
| Acts only on tissues being made. Takes weeks for response. | PTU |
| Taken 2-3 times a day | PTU |
| Adverse rxns include Hypo, Rash, and Transient leukopenia | PTU |
| This is the drug of choice in pregnancy | PTU |
| This should be taken with meals | PTU |
| This drug requires frequent lab testing of TSH, T3, and T4 | PTU |
| A longer half-life in this drug allows for ONCE daily dosing | Tapazole |
| This drug does not work in the periphery | Tapazole |
| Though similar to Tapazole, this drug in contraindicated in pregnant women | Tapazole |
| Effects take longer in this thiomide | Tapazole |
| Oral Radioisotope | Iodide 131 |
| Drug of choice for Hyperthyroidism | Iodide 131 |
| Radiation precautions include... | Distance. Distance from pregs and kids. Preg X usage. |
| This drug is also used in thyroid cancer (Much higher doses) | Iodide 131 |
| This drug is used orally for preoperative thyrotoxic prophylaxis | Lugol's Solution |
| Used as an antiseptic/skin prep | Lugol's solution |
| Absorbs thyroid hormone | Na/K Iodine IV |
| Tx of thyrotoxicosis | Na/K Iodine IV |
| Blocks uptake of radioactive iodine in the environment (Used in Emergencies) | KI 3-10 day usage |
| Decreases heart rate and used to tx tachycardia or other cardiovascular issues. | Beta Blockers |