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mirna

QuestionAnswer
In what shape is mRNA exported? hairpin
What happens when it is exported from the nucleus It loses the polyA tail and 5' head
What does the cropped miRNA interact with? RISC
When there is not an exensive match, what happens? It binds with other mRNA and its translation reduced to eventual degradation
When there is an extensive match, what happens? RISC and miRNA bind to mRNA, it is sliced at a certain site, and then RISC releases with miRNA. Now the mRNA has a cut site
What protein associates with miRNA and mRNA? Argonaute
What are siRNAS? Shirt interfering RNAs that are cut segments of DS RNA
When the siRNAS interact with RITS, what happens? It goes back to the nucleus, is tagged to the end of the RNA being processed in the RNA polymerase
When the siRNAs interact with RISC, what happens? Follows pathway when cut site is created and mRNA is degraded
Created by: neeck
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