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Self and non self
| Question | Answer | ||
|---|---|---|---|
| The surface of human body cells contains ______ and act as _____ in the body of another individual. | large protein molecules | antigen | |
| In mammals, most antigens are ______. | MHC protein | ||
| MHC involved in self and non self is reffered as _____ | Human leukocyte group A (HLA) | ||
| During foatal stage, lymphocytes with receptors (antibody) that could bind to antigen of own cells are quickly identified and destroyed. | No B or T cells can destroy own cells. | ||
| Autoimmune disease | Destruction of lymphocytes is not complete. | These cells attack own body cells. | Maintainance of lymphocytes cells that are unable to respond to self cells enables individual to differentiate self from non self. |
| Tissue graft from third party possesses collection of HLAs different from recipient body cells, | T lymphocytes and antibodies bind with HLAs on foreign cells | Immune response to attack foreign tissue. | |
| Immune cells in body, ____ and ____ cells have self and non self concept. | They differentiate based on HLAs | ||
| The larger the difference in _________ between donor and recipient, the more likely the organ is rejected. | Histocompatibility | ||
| Identical twins have identical ______ | genetic constituent and genome | ||
| Foreign tissue rejection usually involves action of _____, _____ seldom pla role in rejection | T cells | antibodies | |
| Concept of non self | Tissue or organ that regarded by immune system as foreign and is attacked. | ||
| Concept of self | any organ or tissue that is distinguished by the immune system as native tissue and is left alone. |
Created by:
desmondyh
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