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Reassessment 2 drugs

Antineoplastic drugs with side effects

QuestionAnswer
Side effects for antimetabolites Mucositis
Are antimetabolites cell cycle specific? Yes, S-Phase
Drugs in Antimetabolite class 5-FU, Capecitabine, Cytarabine, Gencitabine, 6-MP, 6-Thioguanine, Fludarabine, Cladribine, Pentostatin
Side effects of Vinca Alkaloids/Taxanes (Antimitotic Class) Neurotoxicity
Are Vinca Alkaloids cell cycle specific? Yes, M-Phase
Drugs in Vinca Alkaloid (Antimitotic) class Vincristine, Vinblastine, Vinorelbine
Drugs in Taxane (Antimitotic) class Paclitaxel and Docetaxel
Drugs in Topoisomerase I inhibitors Irinotecan and Topotecan
Side effects of Topoisomerase I inhibitors Diarrhea
Are Topoisomerase inhibitors cell cycle specific? Yes, S-Phase
Drugs in Topoisomerase II inhibitors Teniposide and Etoposide
Side effects of Topoisomerase II inhibitors Myelosuppression
Drugs in Anthracyclines Doxorubicin, Daunorubicin, Idarubicin, Epirubicin, Valrubicin, Mitoxantrone
Side effects for Anthracyclines Cardiotoxicity
Are Antrhracyclines cell cycle specific? No
Drugs in Alkylating Agent class Cyclophosphamide, Busulfan, Mechlorethamine, Melphalan, Thiotepa, Carmustine, Bendamustine, Temolozomide
Side Effects of Akylating Agents Secondary malignancies, nausea/vomiting
Are Alkylating Agents cell cycle specific? No
Drugs in Heavy Metals class Cisplatin, Carboplatin, Oxaplatin
Side effects for Heavy Metals Nephrotoxicity
Are Heavy metals cell cycle specific No
Biologic Antineoplastic drugs Monoclonal antibodies, Hormones, and tyrosine kinase inhibitors
Monoclonal Antibody Mechanism of Action Lysis, drug delivery and inhibits angiogenesis
Hormone Mechanism of Action Blocks production and release of hormone, blocks action of hormone
Tyrosine Kinase Inhibitor Mechanism of Action Blocks cell growth.
Created by: TigerTiff
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