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Antibiotics

exam 1 Medical Bacteriology

QuestionAnswer
Method: Cell wall synthesis Benzylpenicillin
Method: Cell wall synthesis oral bioavailability Ampicillin
Method: Cell wall synthesis Combo of amoxycillin and clavulanic acid that helps amoxycillin stay active and bind to PBP Co-amoxiclav
Method: Cell wall synthesis Combined with B-lactomase inhibitor, also has antipseudomonal activity restricted to ICU achieves high concentrations Piperacillin/ tazocillin
Method: Cell wall synthesis Modification of Benzylpenicillin Flucloxacillin
Method: Cell wall synthesis Bioavailability doubles that of ampicillin Amoxacillin
Gram(+) Broad Spectrum Cephalosporin 1st generation
Gram(-) Broad Spectrum Cephalosporin 2nd generation
Broad Spectrum Cephalosporin 3rd generation
Used in ICU Method: Cell wall synthesis Broad Spectrum, better for gram (-) anaerobes Meropenem
Broad Spectrum Method: Protein Synthesis resistance has a muted porin channel ezyme inhibitor when combined with cilastatin Imipenem
Full gram (+) coverage against cell wall Adds terminal lactose residue at the end of the peptide chain molecule too large Vancomycin
molecule too large Protein synthesis Aminoglycoside
Method: DNA degradation used to affect anaerobes due to neg. redox potential Full broad coverage Metronidazole
Good oral availability and penetration Method: protein synthesis treats anaerobes Clindamycin
Method: RNA synthesis treats TB treats anaerobes well absorbed into tissues Rifampicin
DNA replication Gram (-) coverage fluorinated quinolones Ciprofloxacin
Method: protein synthesis good for treating penicillin allergic patients treats anaerobes Macrolide (erythromyacin)
Broad spectrum inhibits protein synthesis treats genital infections shouldn't be used during pregnancy Tetracyclines
Created by: dollface607
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