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U5: Female Repro
Female Reproductive System
| Question | Answer |
|---|---|
| Organs of female reproductive system | ovaries, oviducts/uterine/fallopian tubes, uterus, vagina, vulva/pudendum |
| Ovaries | female gonads; shape/size of almonds; located in pelvic cavity on lateral sides of uterus; smooth surface before produce/release eggs—scarred/pitted when they begin to produce w/ sexual maturation |
| Broad ligament | support of ovary; sheet/fold of peritoneum that extends from lateral sides of uterus like tent flaps |
| Ovarian ligament | support of ovary; distinct cord w/in broad ligament that extends from ovary to uterus |
| Ovarian cortex | outer region of ovary; contains ovarian follicles |
| Ovarian follicles | multicellular structures in ovarian cortex in which oocytes (immature egg cells) are located; each consists of several follicle cells and one oocyte |
| Primordial follicles | in ovarian cortex; smallest, least mature of different categories of ovarian follicles; follicles from which all subsequent follicle stages are derived |
| Ovarian cycle | activity that occurs in ovary in relation to menstrual cycle; beginning 6-12 primordial follicles begin to grow; usually all degenerate but one—primary follicle, which give rise to secondary follicle, which turns into a vesivular/mature/graafian follicle |
| Follicle stimulating hormone (FSH) | from anterior pituitary gland; at beginning of each ovarian cycle, stimulates primordial follicles to grow |
| Oogenesis | meiosis relative to egg cell production within follicles; produce ova; chromosome number reduced by half from 46 to 23 (dipload to haploid) |
| Corona radiata | follicle cells that cluster most closely around oocyte |
| Zona pellucida | barrier directly coating oocyte which sperm must ultimately penetrate to accomplish fertilization |
| Ovulation | the rupture of a Graafian/mature/vesicular follicle and expulsion of its oocyte; occurs on about day 14 of ovarian cycle; stimulated by surge in secretion of luteinizing hormone (LH) from anterior pituitary gland |
| Luteinizing hormone (LH) | hormone secreted from anterior pituitary gland; stimulates ovulation |
| Corpus luteum | @ ovulation, most cells of ruptured Graafian follicle remain in ovary & are modified to form this structure; secretes estrogens, primarily progesterone; persists ~1st 2 mos pregnancy; if no fertilization, degenerates in about 2 wks forming corpus albicans |
| Corpus albicans | tiny, white, scar-like spot on ovary from unfertilized and unimplanted corpus luteum |
| Uterine tubes/fallopian tubes/oviducts | tubes receive ovulated oocytes from ovary; are usual site of fertilization; each begins near ovary, courses medially to empty into superior uterus |
| Infundibulum | lateral, funnel-shaped portion of uterine tube near ovary; extending from this are the fimbriae |
| Fimbriae | extend from margin of infundibulum; small, finger-like projections coated w/ cilia to draw ovulated egg cells into uterine tube. |
| Ampulla of uterine tube | medial to infundibulum; most common site of fertilization |
| Pelvic Inflammatory Disease (PID) | lack of continuity b/t ovaries & uterine tubes makes female vulnerable to this disease; widespread infection originates in vagina/uterus, spreads to uterine tubes/ovaries, & ultimately peritoneum of pelvic cavity; can cause scar tissue = infertility |
| Ectopic pregnancy | involves implantation of embryo at any site other than uterus; if in uterine tube, can rupture and cause life threatening internal bleeding |
| Salpingectomy | surgical removal of the uterine tube |
| Salpingitis | inflammation of uterine tube |
| Uterus/womb | located in pelvic cavity anterior to rectum, superior to bladder; if never pregnant, about size/shape of inverted pear; usually anteverted, but can become retroverted in older women; regions are body, fundus, cervix |
| Fundus | region of uterus; rounded superior portion |
| Cervix | region of uterus; neck-like, inferior, joined to vagina |
| Body | region of uterus; largest & middle portion that lies between fundus and cervix; bulk of uterine cavity |
| Cervical canal | passes through cervix to open at uterine cavity superiorly via internal os and opens at vagina inferiorly via external os; mucus |
| Broad ligament, lateral cervical (cardinal) ligament, round ligaments | structures that support the uterus; most uterine support provided by muscles of pelvic floor (urogenital and pelvic diaphragm) |
| Broad ligament | supports uterus; sheet-like, extends laterally from uterus like tent flaps |
| Round ligament | supports uterus; cord-like; bind anterior uterus to back of the anterior wall of pelvic cavity |
| Prolapse of uterus | if uterine supporting muscles—urogenital diaphragm, pelvic diaphragm—are torn during childbirth, this condition can occur; uterus falls to an abnormally low position, causing tip of cervix to protrude through vaginal orifice |
| Rectouterine pouch | indentation located b/t rectum and uterus; most inferior part of abdominopelvic cavity, so pus from infections can drain to this pouch |
| Uterine wall | three layers—permetrium, myometrium, endometrium |
| Permetrium | in effect the visceral peritoneum of uterus |
| Myometrium | thick, middle uterine layer made of smooth muscle tissue that provides for strong childbirth contractions |
| Endometrium | innermost layer of uterus; in effect uterine mucosa; consists of lining of epithelium w/ sublayer of connective tissue called lamina propria; embryo burrows into this layer upon fertilization; two specific sublayers—stratum functionalis, stratum basilis |
| Stratum functionalis | sublayer of endometrium; undergoes cyclic thickenings and thinnings in response to varied concentrations of ovarian hormones in blood; lost in menstruation about every 28 days |
| Stratum basilis | sublayer of endometrium; forms new stratum functionalis after each menstruation |
| Uterine cycle | refers to aspect of menstrual cycle that pertains to uterus; series of thickening, thinning phases of endometrium each month in response to altering blood levels |
| Vagina | tube that extends inferiorly from cervix of uterus; lies anterior to rectum, posterior to urethra; "birth canal"; mucosa of stratified squamous epithelium for abrasion protection and underlying lamina propria; acidic pH due to beneficial resident bacteria |
| Vaginal orifice | vagina’s external opening |
| Hymen | near vaginal orifice, mucosa elaborates to form partial partition; membrane may be ruptured during exercise, insertion of tampon, or sexual intercourse |
| Fornix of the vagina | indentation where superior part of vagina encircles tip of uterine cervix |
| External genitalia/vulva/pudendum | structures include mons pubis, labia majora, labia minora, vestibule features |
| Mons pubis | fatty, rounded pad overlying pubic symphasis; will grow hair at puberty |
| Labia majora | extend posteriorly from mons pubis; two hair covered folds of skin; enclose labia minora |
| Labia minora | two hairless folds of skin enclosed by labia majora; enclose vestibule |
| Vestbule | area between labia minora; house external urethral orifice and vaginal orifice |
| Greater vestibular (Bartholin’s) glands | flanking vaginal orifice; paired, pea sized glands that provide lubricating mucus during sexual excitation |
| Clitoris | located where two labia minora meet at anterior point of vestibule; composed mainly of erectile tissue; sensitive and swells w/ blood during stimulation |
| Female Perineum | floor of pelvis; in exact center lies central tendon/perineal body |
| Central tendon/perineal body | center of perineum; structure serves as point of insertion for most muscles that support the pelvic floor/uterus; can be torn by infant’s head during delivery |
| Episiotomy | performed during delivery to in attempt to avoid tearing of central tendon/perineal body; vaginal orifice is widened by posterior cut from it into clinical perineum at time baby’s head appears at vestibule |
| Mammary glands/breasts | only function in lactating females when produce milk to nourish an infant in response to hormonal stimulation; internally has 15-25 lobes separated by adipose tissue and suspensory ligaments of breasts |
| Lactiferous ducts | largest ducts in nipple; milk passes from lobules through progressively larger ducts until it reaches these |
| Fertilization | occurs when nucleus of sperm unites w/ nucleus of egg; sperm reaches oocyte; binds to zona pellucida, releases digestive enzymes, which eat away at zona pellucida until slit is made which sperm can squeeze through |
| Cleavage | series of mitotic cell divisions in fertilized egg/zygote; first forming morula (solid ball of cells) and then forming blastocyst (hollow ball of cells) |
| Blastocyst | hollow ball of cells formed in cleavage; very early aspect of embryonic development consisting of 2 grps—inner cell mass, trophoblast |
| Inner cell mass | group of blastocyst; will form body of embryo |
| Trophoblast | group of blastocyst; will form placenta |
| Implantation | process by which blastocyst burrows into endometrium of uterus; about 6 days after fertilization; takes about a week to be completed |
| Placenta | serves as respiratory, digestive, urinary systems for fetus; permeable, but blocks passage of most bacteria from mother to fetus; many viruses and drugs can pass through placenta from mother to fetus |
| Placenta previa | condition in which embryo implants in inferior aspect of uterine wall; consequently placenta may cover internal os of cervical canal; associated w/bleeding during last 3 mos of pregnancy; bed rest prescribed; can interfere w/ fetal development |
| Placental abruption | condition in which placenta is in normal position, but becomes partly separated from uterine wall prior to birth; also produces vaginal bleeding during pregnancy; can interfere w/ fetal development |
| Puberty | period of life b/t ~ages 10-15 when reproductive organs grow to adult size & reproduction becomes possible; due to rising levels of estrogens/testosterones |
| Menopause | occurs ages ~46-54; associated w/ decreased activity of ovaries; ovulation ceases, stop producing estrogen, causing repro organs/breasts to atrophy, bone mass declines, blood cholesterol levels slowly rise, increasing risk of cardiovascular disorders |
| Ovarian cancer | cancer that arises from epithelial cells on surface of ovary |
| Endometrial cancer | cancer that arises from epithelium of endometrium; unfortunately postmenopausal estrogen-replacement therapy increases risk of this cancer |
| Cervical cancer | cancer that arises from epithelial cells that cover tip of cervix; pap smear is best detection method |
| Breast cancer | cancer that arises from epithelium of ducts in lobules of breasts; occurs in ~1 / every 8 women; risk factors are family history, post-menopausal hormone replacement therapy; often spreads rapidly via metastasizing from breast through lymphatic vessels |
| Fibroids | slow growing, benign tumors in wall of uterus |
| Hysterectomy | surgical removal of uterus, most frequently done to remove fibroids |
| Endometriosis | condition in which fragments of endometrial tissue are located at a site outside of uterus such as uterine tubes, ovaries, peritoneum of pelvic cavity; can be painful due to thickening/thinning of out of place endometrial tissue |
| Tubal ligation | tying and/or cutting the uterine tubes as a form of birth control |