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Microbiology exam 1a
Structure and function
| Question | Answer |
|---|---|
| First microscope | Leuvenhook |
| Waksman | discovered streptomycin, coined antibiotic |
| Tetrapeptide | L-Alanine, D-glutamate, L-lysine, and D-alanine in gram positive ... L-Alanine, D-glutamate, MESO-diaminopimelic acid, D-alanine in gram negative |
| Crosslinking | between 3rd and 4th adjacent amino acids. links tetrapeptide via pentaglycine bridge in Gram+, in gram negative cross linking occurs less frequently and directly between diaminopimellic acid and D-alanine |
| LPS | specific to Gram-, 3 parts, O-antigen (specific to strain), core, Lipid-A |
| Transglycosylation | UDP binds NAG, bactoprenol binds NAM, NAG-NAM-pentaglycine-bactoprenol moves across membrane for association |
| Flagella | 3 parts, hook,body,filament. counterclockwise toward attractant, clockwise tumble away. Trichous=flagellum |
| Stages of sporogenesis | DNA replicates, membrane invaginates-septum forms, forespore develops, DPA/spore-cellwall/cortex forms and forespore engulfed, cysteine rich spore coat forms |