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EMT-P Pharmacology

Drug - classes and actions

Schedule I High Abuse Potential No Recognized Medical Use Heroin/LSD/Mescaline
Schedule II Written Prescription Required High Abuse Potential Codeine/Morphine/Meperidine Amphetamines/Phenmetrazine
Schedule III High Abuse Potential Prescription Required Opiates/Stimulants/Depressants/Anabolic Steroids
Schedule IV Prescription Required Low Abuse Potential Opiates/Stimulants/Depressants
Schedule V Dispensed as any non-opiate Prescription Low Abuse Potential
Assay Test that determines the amount and purity of a drug
Bioequivalent Relative therapeutic effectiveness of chemically equivalent drugs
Drug Absorption Dependent on: 1.Solubility of drug 2.Concentration 3.Ph of drug 4.Site of absorption 5.Absorption area of site 6.Blood supply to area 7.Bioavailability
Distribution Affected by: 1.Cardiovascular function 2.Regional blood flow 3.Drug storage reservoirs 4.Physiological barriers
Biotransformation Name given to the metabolism of drugs Has one of two effects on drugs: 1.transforms the drug into a more or less active metabolite 2.Makes the drug more water soluble to facilitate excretion
First Pass Effect Process by which enteral drugs are absorbed via the GI track and through the liver, partially or completely inactivating the drug.
Elimination Process of eliminating the drugs Affected by: 1.Drugs Half-life 2.Accumulation of the drug 3.Clearance 4.Onset, Peak and Duration
Half-Life Time required for the total amount of a drug to be diminished by one-half.
Accumulation Through re-administration of maintenance doses, achieves a steady state of drug availability, although fluctuates within a given range
Clearance Refers to the removal of a drug from the body
Onset of action Time when sufficient amount of a drug is absorbed and distributed to obtain therapeutic effects
Peak Concentration As more drug is absorbed, more is distributed and available to obtain therapeutic effects - Peak Concentration
Duration of Action Is the length of time that drug concentration is sufficient enough to produce the therapeutic effect
Affinity The force of attraction between a drug and a receptor
Efficacy The ability of a drug to cause the expected response
Created by: clementroger